Immunology. Orchestrating inflammasomes.
作者信息
Franchi Luigi, Núñez Gabriel
机构信息
Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
出版信息
Science. 2012 Sep 14;337(6100):1299-300. doi: 10.1126/science.1229010.
Abstract
摘要
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本文引用的文献
1
Phosphorylation of NLRC4 is critical for inflammasome activation.NLRC4 的磷酸化对于炎症小体的激活至关重要。
Nature. 2012 Oct 25;490(7421):539-42. doi: 10.1038/nature11429. Epub 2012 Aug 12.
2
Sensing and reacting to microbes through the inflammasomes.通过炎症小体感知和应对微生物。
Nat Immunol. 2012 Mar 19;13(4):325-32. doi: 10.1038/ni.2231.
3
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.NLRC4 炎性小体受体识别细菌鞭毛蛋白和 III 型分泌系统。
Nature. 2011 Sep 14;477(7366):596-600. doi: 10.1038/nature10510.
4
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.先天免疫通过 NAIPs 识别细菌配体决定了炎症小体的特异性。
Nature. 2011 Aug 28;477(7366):592-5. doi: 10.1038/nature10394.
5
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. toll 样受体及其在感染和免疫中与其他先天受体的相互作用。
Immunity. 2011 May 27;34(5):637-50. doi: 10.1016/j.immuni.2011.05.006.
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A receptor-like cytoplasmic kinase phosphorylates the host target RIN4, leading to the activation of a plant innate immune receptor.一种受体样细胞质激酶磷酸化宿主靶标 RIN4，导致植物先天免疫受体的激活。
Cell Host Microbe. 2011 Feb 17;9(2):137-46. doi: 10.1016/j.chom.2011.01.010.
7
Specific threonine phosphorylation of a host target by two unrelated type III effectors activates a host innate immune receptor in plants.两种不相关的 III 型效应蛋白对宿主靶蛋白的特定苏氨酸磷酸化激活了植物中的一种宿主先天免疫受体。
Cell Host Microbe. 2011 Feb 17;9(2):125-36. doi: 10.1016/j.chom.2011.01.009.
8
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome.通过 NLRC4 炎性小体对 III 型分泌装置的先天免疫检测。
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The plant immune system.植物免疫系统。
Nature. 2006 Nov 16;444(7117):323-9. doi: 10.1038/nature05286.
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Distinct domains in the ARC region of the potato resistance protein Rx mediate LRR binding and inhibition of activation.马铃薯抗性蛋白Rx的ARC区域中不同的结构域介导富含亮氨酸重复序列（LRR）结合及激活抑制。
Plant Cell. 2006 Aug;18(8):2082-93. doi: 10.1105/tpc.106.042747. Epub 2006 Jul 14.
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