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Immunology. Orchestrating inflammasomes.

作者信息

Franchi Luigi, Núñez Gabriel

机构信息

Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

出版信息

Science. 2012 Sep 14;337(6100):1299-300. doi: 10.1126/science.1229010.

Abstract
摘要

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本文引用的文献

1
Phosphorylation of NLRC4 is critical for inflammasome activation.
Nature. 2012 Oct 25;490(7421):539-42. doi: 10.1038/nature11429. Epub 2012 Aug 12.
2
Sensing and reacting to microbes through the inflammasomes.
Nat Immunol. 2012 Mar 19;13(4):325-32. doi: 10.1038/ni.2231.
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The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
Nature. 2011 Sep 14;477(7366):596-600. doi: 10.1038/nature10510.
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Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.
Nature. 2011 Aug 28;477(7366):592-5. doi: 10.1038/nature10394.
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Toll-like receptors and their crosstalk with other innate receptors in infection and immunity.
Immunity. 2011 May 27;34(5):637-50. doi: 10.1016/j.immuni.2011.05.006.
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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome.
Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3076-80. doi: 10.1073/pnas.0913087107. Epub 2010 Feb 1.
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The plant immune system.
Nature. 2006 Nov 16;444(7117):323-9. doi: 10.1038/nature05286.
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Distinct domains in the ARC region of the potato resistance protein Rx mediate LRR binding and inhibition of activation.
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