Tufts Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA.
Science. 2012 Sep 14;337(6100):1309-12. doi: 10.1126/science.1223805.
Rinderpest is only the second infectious disease to have been globally eradicated. In the final stages of eradication, the virus was entrenched in pastoral areas of the Greater Horn of Africa, a region with weak governance, poor security, and little infrastructure that presented profound challenges to conventional control methods. Although the eradication process was a development activity rather than scientific research, its success owed much to several seminal research efforts in vaccine development and epidemiology and showed what scientific decision-making and management could accomplish with limited resources. The keys to success were the development of a thermostable vaccine and the application of participatory epidemiological techniques that allowed veterinary personnel to interact at a grassroots level with cattle herders to more effectively target control measures.
牛瘟是全球第二种被根除的传染病。在根除的最后阶段，病毒在大非洲之角的牧区扎根，该地区治理薄弱，安全状况差，基础设施匮乏，给传统的控制方法带来了巨大挑战。尽管根除过程是一项发展活动，而不是科学研究，但它的成功在很大程度上归功于疫苗开发和流行病学方面的几项开创性研究工作，这表明在有限的资源下，科学决策和管理能够取得什么成就。成功的关键是开发出一种耐热疫苗，并应用参与式流行病学技术，使兽医人员能够在基层与牧民互动，更有效地针对控制措施。
