局限性掌跖角化过度症：氟尿嘧啶乳膏治疗成功。
Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream.
机构信息
Dermatohistological Laboratory and Private Practice, Postfach 4145, 90021 Nuernberg, Germany.
出版信息
Dermatol Ther (Heidelb). 2011 Sep;1(1):11-4. doi: 10.1007/s13555-011-0002-2. Epub 2011 May 4.
Abstract
INTRODUCTION
The pathogenesis of circumscribed palmar hypokeratosis (CPH) is still controversial, and to date there is no treatment of choice.
METHODS
We report on a patient with CPH responding to treatment with fluorouracil cream.
RESULTS
The clinical course and histopathological features in our observation point towards the possibility of an underlying squamous cell carcinoma in situ presenting as CPH.
CONCLUSION
We suggest that fluorouracil cream treatment should be considered as a therapeutic option in cases of CPH.
摘要
简介
局限性掌跖角化病（CPH）的发病机制仍存在争议，迄今为止尚无首选治疗方法。
方法
我们报告了一例 CPH 患者对氟尿嘧啶乳膏治疗有反应的病例。
结果
我们的观察结果提示，CPH 可能存在潜在的鳞状细胞原位癌。
结论
我们建议氟尿嘧啶乳膏治疗应作为 CPH 的一种治疗选择。
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