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Diminished superoxide anion generation by reduced 5-iminodaunorubicin relative to daunorubicin and the relationship to cardiotoxicity of the anthracycline antitumor agents.

作者信息

Lown J W, Chen H H, Plambeck J A, Acton E M

出版信息

Biochem Pharmacol. 1979 Sep 1;28(17):2563-8. doi: 10.1016/0006-2952(79)90027-3.

DOI:10.1016/0006-2952(79)90027-3
PMID:229856
Abstract
摘要

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1
Diminished superoxide anion generation by reduced 5-iminodaunorubicin relative to daunorubicin and the relationship to cardiotoxicity of the anthracycline antitumor agents.
Biochem Pharmacol. 1979 Sep 1;28(17):2563-8. doi: 10.1016/0006-2952(79)90027-3.
2
5-Iminodaunorubicin. Reduced cardiotoxic properties in an antitumor anthracycline.5-亚氨基柔红霉素。一种抗肿瘤蒽环类药物，其心脏毒性有所降低。
J Med Chem. 1979 Jan;22(1):36-9. doi: 10.1021/jm00187a009.
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6
Toxicologic screening of daunorubicin (NSC-82151), adriamycin (NSC-123127), and their derivatives in rats.
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