Department of Biology and Environmental Protection, Poznan University of Medical Sciences, Poznań, Poland.
Environ Toxicol Pharmacol. 2012 Nov;34(3):651-60. doi: 10.1016/j.etap.2012.08.005. Epub 2012 Aug 30.
Cylindrospermopsin (CYN) is a secondary metabolite produced by several cyanobacteria species. Its potential effect on human health includes liver, kidneys, lungs, spleen and intestine injuries. CYN can be cyto- and genotoxic to a variety of cell types. Occurrence and expansion of species able to synthesize CYN in European water bodies has been recently reported and raised awareness of potential harm to human health. Therefore, surface water of different human use should be monitored for the presence of toxic species of blue-green algae. This paper aims to describe the distribution of CYN producers in Europe and the potential effects of the toxin on human health according to the current state of knowledge.
柱孢藻毒素(CYN)是几种蓝藻产生的次生代谢产物。其对人类健康的潜在影响包括肝、肾、肺、脾和肠损伤。CYN 对多种细胞类型具有细胞毒性和遗传毒性。最近有报道称,能够在欧洲水体中合成 CYN 的物种的出现和扩张引起了人们对人类健康潜在危害的关注。因此,应监测不同用途的地表水是否存在有毒蓝藻。本文旨在根据现有知识描述 CYN 生产者在欧洲的分布情况以及毒素对人类健康的潜在影响。