Choi Sung Yong, Cho Yang-Sun, Lee Nak Joon, Lee Jungbok, Chung Won-Ho, Hong Sung Hwa
Department of Otolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Arch Otolaryngol Head Neck Surg. 2012 Sep;138(9):840-5. doi: 10.1001/archoto.2012.1800.
To assess the factors affecting health-related quality of life (HRQOL) after ear surgery in patients with chronic otitis media (COM).
Prospective questionnaire-based outcome study.
Tertiary care institution.
The study population comprised 205 patients aged 21 to 67 years referred for ear surgery owing to COM with or without cholesteatoma between November 2009 and March 2011.
The ear surgery for COM included tympanoplasty, with or without mastoidectomy. The Korean version of the Chronic Ear Survey (K-CES), a disease-specific outcome survey, was administered before and 12 months after surgery.
The primary outcome measures were the total score and subscale score, including an activity restriction-based subscale, symptom subscale, and medical resource utilization subscale. The scores were analyzed with disease- and patient-related factors affecting health-related quality of life.
Of the 205 patients enrolled, complete data from 156 patients were available for this study. The K-CES score in patients with COM improved after ear surgery in total and in all subscales of the K-CES (P < .001). In univariable analysis, poor improvement in total K-CES score was more likely to occur after ear surgery in patients with postoperative complications, diabetes mellitus, hearing loss as a chief complaint, lower air conduction threshold in postoperative audiometry, and a high level of education and in those who underwent canal wall down mastoidectomy (P < .05). Multivariable analysis using multiple linear regression revealed that the occurrence of complications, presence of diabetes mellitus, level of education, and postoperative air conduction thresholds were independent factors for poor improvement in total K-CES score (P < .05).
Recognition of factors that have significant relation with subjective outcomes may help surgeons to identify patients who are prone to have a lower satisfaction and provide useful information in preoperative counseling.
评估影响慢性中耳炎(COM)患者耳部手术后健康相关生活质量(HRQOL)的因素。
基于问卷的前瞻性结局研究。
三级医疗机构。
研究人群包括2009年11月至2011年3月期间因COM伴或不伴胆脂瘤而转诊接受耳部手术的205例年龄在21至67岁之间的患者。
COM的耳部手术包括鼓室成形术,可伴或不伴乳突切除术。在手术前和术后12个月进行特定疾病结局调查——韩文版慢性耳部调查(K-CES)。
主要结局指标为总分及各子量表得分,包括基于活动受限的子量表、症状子量表和医疗资源利用子量表。对得分进行分析,探讨影响健康相关生活质量的疾病和患者相关因素。
在纳入的205例患者中,有156例患者的完整数据可用于本研究。COM患者耳部手术后K-CES总分及所有子量表得分均有所改善(P <.001)。在单变量分析中,术后有并发症、糖尿病、以听力损失为主诉、术后听力测定气导阈值较低、受教育程度较高以及接受开放式乳突切除术的患者,耳部手术后K-CES总分改善较差的可能性更大(P <.05)。使用多元线性回归的多变量分析显示,并发症的发生、糖尿病的存在、受教育程度和术后气导阈值是K-CES总分改善较差的独立因素(P <.05)。
认识到与主观结局有显著关系的因素可能有助于外科医生识别出满意度较低的患者,并在术前咨询中提供有用信息。