Service de Chirurgie Hépatobiliaire et Digestive, Hôpital Pontchaillou, Centre Hospitalier Universitaire, Université de Rennes 1, Rennes, France.
Surg Today. 2013 Jul;43(7):727-31. doi: 10.1007/s00595-012-0328-0. Epub 2012 Sep 18.
The aim of the current study was to evaluate the outcome after primary repair in comparison to other surgical treatments and the advantage of reinforcing the sutures with an absorbable polyglactin 910 prosthesis.
All esophageal perforations surgically managed in this institution from January 1985 through April 2009 (n = 40) were retrospectively analyzed. Patients that underwent surgery with primary sutures (group A, n = 24) were compared with patients that received other surgical procedures (group B, n = 16). The time to initiate treatment (within or after the first 24 h) and if the suture was reinforced with a polyglactin 910 mesh were also analyzed in group A patients.
The outcome was more favorable in group A than group B in terms of time in the intensive care unit (p = 0.005), and rate of reoperation (p = 0.005). There was no difference in the outcome after the primary suture with or without mesh reinforcement, although the rate of fistulization was lower in patients with a mesh (17 vs. 50 %, p = 0.19).
Primary repair has a better outcome than other surgical treatment, even when performed more than 24 h after symptom onset, but not later than 48 h. Reinforcing the sutures with an absorbable polyglactin 910 mesh therefore seems to improve the outcome.
本研究旨在评估初次修复的结果,并与其他手术治疗方法进行比较,同时评估使用可吸收聚甘醇酸 910 补片加固缝合线的优势。
回顾性分析 1985 年 1 月至 2009 年 4 月期间本院收治的所有经手术治疗的食管穿孔患者(n=40)。将接受初次缝合手术的患者(A 组,n=24)与接受其他手术治疗的患者(B 组,n=16)进行比较。还分析了 A 组患者中手术开始时间(24 小时内或 24 小时后)以及缝合线是否用聚甘醇酸 910 网片加固。
A 组患者在重症监护病房的时间(p=0.005)和再次手术率(p=0.005)方面的结果均优于 B 组。初次缝合后是否使用网片加固,结果没有差异,尽管使用网片的患者瘘管形成率较低(17%比 50%,p=0.19)。
初次修复的结果优于其他手术治疗方法,即使在症状出现后 24 小时以上、但不超过 48 小时进行手术,也是如此。使用可吸收聚甘醇酸 910 网片加固缝合线可改善结果。