Skin Research Center, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dermatol Surg. 2012 Oct;38(10):1662-7. doi: 10.1111/j.1524-4725.2012.02541.x. Epub 2012 Sep 18.
Despite their prevalence, there is a paucity of information in the medical literature on the treatment of atrophic chickenpox scars.
To evaluate the efficacy and safety of using the chemical reconstruction of skin scar technique for the treatment of atrophic facial chickenpox scars.
One hundred patients (mean age 23 years; Fitzpatrick skin types II-IV) were treated with focal chemical peeling with 70% trichloroacetic acid (TCA) for a maximum of six sessions. Improvement rate, frequency of adverse events and patient satisfaction were assessed.
Five hundred thirty-three peeling sessions in 100 consecutive patients were performed. Final assessment at 12-week follow-up visit after the last treatment revealed improvement in 95% of patients: mild improvement in 12 cases, moderate improvement in 42 cases, and marked improvement in 41 cases. The appearance of scars did not change in five patients. Seventy-nine patients expressed moderate to high satisfaction with the results. Post-treatment side effects were mild and transient, resolving gradually within the study period.
Focal peeling with high-concentration TCA appears to be a safe and effective alternative in the treatment of atrophic facial chickenpox scars.
尽管萎缩性水痘疤痕很常见，但医学文献中关于其治疗方法的信息却很少。
评估使用皮肤疤痕化学重建技术治疗面部萎缩性水痘疤痕的疗效和安全性。
100 例患者（平均年龄 23 岁；Fitzpatrick 皮肤类型 II-IV）接受了最大 6 次的 70%三氯乙酸（TCA）局灶性化学脱皮治疗。评估了改善率、不良事件发生频率和患者满意度。
在 100 例连续患者中进行了 533 次脱皮治疗。最后一次治疗后 12 周的随访评估显示，95%的患者有改善：12 例轻度改善，42 例中度改善，41 例明显改善。5 名患者的疤痕外观无变化。79 名患者对治疗结果表示中度至高度满意。治疗后的副作用轻微且短暂，在研究期间逐渐缓解。
高浓度 TCA 的局灶性脱皮似乎是治疗面部萎缩性水痘疤痕的一种安全有效的替代方法。
