2nd Dermatology Department, Andreas Sygros Hospital, Athens, Greece.
J Cosmet Dermatol. 2013 Sep;12(3):204-9. doi: 10.1111/jocd.12044.
Periorbital dark circles are relatively common, affecting individuals regardless of age, sex, and race. Available treatment includes bleaching creams, topical retinoid acid, chemical peels, laser therapy, autologous fat transplantation - injectable fillers, surgery (blepharoplasty), and chemical peeling.
To evaluate the efficacy of a combination of trichloroacetic TCA 3.75% and lactic acid 15% on improving the periorbital hyperpigmentation.
PATIENTS/METHODS: Thirty patients with periorbital dark circles and skin types II, III, or IV were included in the study. Chemical peeling was performed every week for a series of four treatments. The effect was photo-documented, and a patient's and physician's global assessment was evaluated.
Almost all the patients showed significant esthetic improvement. Physicians assessed a fair, good, or excellent improvement in 93.3% of the patients. Patient's global assessment rated a fair, good, or excellent response in 96.7% of the patients. The procedure itself had only mild and temporary adverse effects, such as erythema, edema, frosting, dryness, and telangiectasias. The effects of treatment remained for at least 4-6 months in the majority of patients with appropriate sun protection.
The combination of trichloroacetic TCA 3.75% and lactic acid 15% showed encouraging results on improving periorbital hyperpigmentation.
眶周黑眼圈较为常见，无论年龄、性别和种族，都会影响个体。现有的治疗方法包括漂白霜、局部维 A 酸、化学换肤、激光治疗、自体脂肪移植-注射填充剂、手术（眼睑成形术）和化学脱皮。
评估三氯乙酸 TCA 3.75%和乳酸 15%联合用于改善眶周色素沉着过度的疗效。
患者/方法：30 例眶周黑眼圈伴 II、III 或 IV 型皮肤的患者纳入本研究。每周进行一次化学换肤，共进行 4 次系列治疗。对效果进行拍照记录，并评估患者和医生的整体评估。
几乎所有患者均显示出明显的美容改善。93.3%的医生评估为改善效果为一般、良好或极好。96.7%的患者对治疗效果的整体评估为一般、良好或极好。该过程本身仅有轻度且短暂的不良反应，如红斑、水肿、结霜、干燥和毛细血管扩张。在大多数患者中，只要有适当的防晒措施，治疗效果至少可维持 4-6 个月。
三氯乙酸 TCA 3.75%和乳酸 15%联合使用在改善眶周色素沉着过度方面显示出令人鼓舞的效果。
