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一名未服用青霉胺的患者出现寻常型天疱疮合并类风湿关节炎

Pemphigus Vulgaris Associated with Rheumatoid Arthritis in a Patient not Taking Penicillamine.

作者信息

Gholizadeh Narges, Taghavi Zenouz Ali, Eslami Hossein

机构信息

Assistant Professor, Department of Oral Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

J Dent Res Dent Clin Dent Prospects. 2012 Winter;6(1):33-5. doi: 10.5681/joddd.2012.008. Epub 2012 Mar 13.

DOI:10.5681/joddd.2012.008
PMID:22991633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3442446/
Abstract

D-penicillamine is one of the disease-modifying anti-rheumatic drugs (DMARDs). Drug-induced pemphigus is not fre-quently associated with D-penicillamine, and to date, the number of reported cases is about a hundred. Most reports of D-penicillamine-induced pemphigus vulgaris are in patients with rheumatoid arthritis. It has rarely been reported in patients not taking D-penicillamine. We report a case of pemphigus vulgaris in a 48-year-old female patient with rheumatoid arthri-tis, not taking penicillamine.

摘要

青霉胺是改善病情抗风湿药(DMARDs)之一。药物性天疱疮与青霉胺的关联并不常见,迄今为止,报告的病例数约为100例。大多数关于青霉胺诱发寻常型天疱疮的报告都见于类风湿关节炎患者。在未服用青霉胺的患者中鲜有报道。我们报告一例48岁患类风湿关节炎但未服用青霉胺的女性寻常型天疱疮患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/3442446/674d58bfc8e8/joddd-6-33-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/3442446/03f00f9c837d/joddd-6-33-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/3442446/4b406e3a5876/joddd-6-33-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/3442446/674d58bfc8e8/joddd-6-33-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/3442446/03f00f9c837d/joddd-6-33-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/3442446/4b406e3a5876/joddd-6-33-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa9e/3442446/674d58bfc8e8/joddd-6-33-g003.jpg

相似文献

1
Pemphigus Vulgaris Associated with Rheumatoid Arthritis in a Patient not Taking Penicillamine.一名未服用青霉胺的患者出现寻常型天疱疮合并类风湿关节炎
J Dent Res Dent Clin Dent Prospects. 2012 Winter;6(1):33-5. doi: 10.5681/joddd.2012.008. Epub 2012 Mar 13.
2
D-penicillamine and gold salt treatments were complicated by myasthenia and pemphigus, respectively, in the same patient with rheumatoid arthritis.在同一位类风湿关节炎患者中,D-青霉胺和金盐治疗分别出现了重症肌无力和天疱疮并发症。
Rheumatol Int. 1995;15(3):95-7. doi: 10.1007/BF00302124.
3
Bucillamine-induced pemphigus vulgaris in a patient with rheumatoid arthritis and polymyositis overlap syndrome.青霉胺诱发的寻常型天疱疮见于一名患有类风湿关节炎和多发性肌炎重叠综合征的患者。
J Korean Med Sci. 2006 Jun;21(3):585-7. doi: 10.3346/jkms.2006.21.3.585.
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[D-penicillamine-induced pemphigus].
Dermatologica. 1980;160(5):297-310.
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[Penicillamine-induced pemphigus].
Hautarzt. 1987 Sep;38(9):548-52.
6
Pemphigus vulgaris induced by D-penicillamine therapy in a patient with systemic sclerosis.
J Am Acad Dermatol. 2000 Feb;42(2 Pt 1):297-9. doi: 10.1016/S0190-9622(00)90146-4.
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[D-penicillamine-induced pemphigus, polymyositis and myasthenia].
Ann Dermatol Venereol. 1999 Feb;126(2):153-6.
8
[Superficial pemphigus during the treatment of rheumatoid polyarthritis with D-penicillamine and piroxicam (Feldene)].
Dermatologica. 1985;170(6):297-301.
9
Minimal change nephropathy and pemphigus vulgaris associated with penicillamine treatment of rheumatoid arthritis.
Clin Nephrol. 1988 May;29(5):267-70.
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[Pemphigus induced by D-penicillamine in rheumatoid arthritis. Study of 5 cases and systematic study of anti-intercellular substance antibodies of the skin in the course of treatment].
Nouv Presse Med. 1975 Dec 20;4(44):3125-8.

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Autoimmune pemphigus: difficulties in diagnosis and the molecular mechanisms underlying the disease.自身免疫性天疱疮:诊断难点及疾病的分子机制
Front Immunol. 2025 Mar 3;16:1481093. doi: 10.3389/fimmu.2025.1481093. eCollection 2025.
2
Pemphigus: trigger and predisposing factors.天疱疮:触发因素和诱发因素。
Front Med (Lausanne). 2023 Dec 27;10:1326359. doi: 10.3389/fmed.2023.1326359. eCollection 2023.
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Seborrheic Pemphigus, Antigen Mimicry and the Subsequent-Wrong Diagnostic and Therapeutic Approach?脂溢性天疱疮、抗原模拟及随后错误的诊断和治疗方法?

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