Gholizadeh Narges, Taghavi Zenouz Ali, Eslami Hossein
Assistant Professor, Department of Oral Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
J Dent Res Dent Clin Dent Prospects. 2012 Winter;6(1):33-5. doi: 10.5681/joddd.2012.008. Epub 2012 Mar 13.
D-penicillamine is one of the disease-modifying anti-rheumatic drugs (DMARDs). Drug-induced pemphigus is not fre-quently associated with D-penicillamine, and to date, the number of reported cases is about a hundred. Most reports of D-penicillamine-induced pemphigus vulgaris are in patients with rheumatoid arthritis. It has rarely been reported in patients not taking D-penicillamine. We report a case of pemphigus vulgaris in a 48-year-old female patient with rheumatoid arthri-tis, not taking penicillamine.
青霉胺是改善病情抗风湿药(DMARDs)之一。药物性天疱疮与青霉胺的关联并不常见,迄今为止,报告的病例数约为100例。大多数关于青霉胺诱发寻常型天疱疮的报告都见于类风湿关节炎患者。在未服用青霉胺的患者中鲜有报道。我们报告一例48岁患类风湿关节炎但未服用青霉胺的女性寻常型天疱疮患者。