Sasadeusz J, Buchanan M, Speed B
Fairfield Hospital, Fairfield, Melbourne, Victoria, Australia.
J Infect. 1990 Jan;20(1):65-8. doi: 10.1016/s0163-4453(90)92390-7.
The reactive or virus-associated haemophagocytic syndrome (RHS) has been described in association with several different infections and is regarded as clinically and pathologically distinct from malignant histiocytosis. A case is described of this syndrome in a 30-year-old HIV-antibody positive homosexual male who presented with fever, pancytopenia, lymphadenopathy, and massive splenomegaly. The fever and haematological abnormalities resolved following splenectomy, and the patient remains well after 12 months. Prominent histiocytic haemophagocytosis was seen in both the spleen and an abdominal lymph node. Exhaustive tests failed to demonstrate any infectious agent other than human immunodeficiency virus, indicating this to be a case of this syndrome occurring in association with HIV infection.
反应性或病毒相关性噬血细胞综合征（RHS）已被描述与多种不同感染相关，并且在临床和病理上被认为与恶性组织细胞增多症不同。本文描述了一名30岁HIV抗体阳性的同性恋男性患此综合征的病例，该患者出现发热、全血细胞减少、淋巴结病和巨脾。脾切除术后发热和血液学异常得以缓解，患者在12个月后情况良好。在脾脏和一个腹部淋巴结中均可见显著的组织细胞噬血现象。详尽检查未能发现除人类免疫缺陷病毒以外的任何感染因子，表明这是一例与HIV感染相关的该综合征病例。
