Domínguez R
Laboratory of Biology of Reproduction, Escuela Nacional de Estudios Profesionales Zaragoza, UNAM, D.F., Mexico.
J Endocrinol. 1990 Jan;124(1):43-5. doi: 10.1677/joe.0.1240043.
Differences were observed in the ovulation rates of the right and left ovaries in response to unilateral lesions of the cervico-vaginal plexus (CVP) followed by pseudopregnancy or by anaesthesia of the CVP induced with panthocaine plus adrenaline (right ovary 6.7 +/- 0.4 (S.E.M.) vs left ovary 4.6 +/- 0.9; P less than 0.05). Pseudopregnancy (days showing a dioestrous smear after copulation with a vasectomized male before an oestrous smear following a pro-oestrous one) lasted longer in rats with a lesion in the CVP than in a control pseudopregnant group (14.9 +/- 0.5 vs 11.2 +/- 0.5; P less than 0.01). Anaesthesia of the CVP performed on each day of the oestrous cycle did not modify the ovulation rate compared with laparotomized animals. Both laparotomy and anaesthesia of the CVP performed on oestrus or day 1 of dioestrus blocked ovulation but when they were performed on day 2 of dioestrus or pro-oestrus they failed to do so (laparotomy 9/18 vs 12/14, P less than 0.05; anaesthesia of CVP 3/11 vs 17/17, P less than 0.05). The number of ova shed by the left ovary in animals with anaesthetized CVP was lower than by the right ovary (4.5 +/- 0.6 vs 6.2 +/- 0.5; P less than 0.05). These results add further support to the idea that the CVP participates in the regulation of ovulation rate, and that the left ovary is less adaptable than the right when innervation is challenged.
在对子宫颈 - 阴道丛（CVP）进行单侧损伤后，通过假孕或用潘托卡因加肾上腺素诱导CVP麻醉，观察到左右卵巢的排卵率存在差异（右侧卵巢6.7±0.4（标准误）对左侧卵巢4.6±0.9；P<0.05）。假孕（在动情前期涂片后与输精管切除的雄性交配，出现双相期涂片后的天数）在CVP损伤的大鼠中比在对照假孕组持续时间更长（14.9±0.5对11.2±0.5；P<0.01）。与剖腹手术的动物相比，在动情周期的每一天对CVP进行麻醉不会改变排卵率。在发情期或双相期第1天进行剖腹手术和CVP麻醉均可阻断排卵，但在双相期第2天或动情前期进行则不能阻断排卵（剖腹手术9/18对12/14，P<0.05；CVP麻醉3/11对17/17，P<0.05）。CVP麻醉的动物中左侧卵巢排出的卵子数量低于右侧卵巢（4.5±0.6对6.2±0.5；P<0.05）。这些结果进一步支持了CVP参与排卵率调节的观点，并且当神经支配受到挑战时，左侧卵巢比右侧卵巢适应性更差。
