Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.
Int J Dermatol. 2012 Oct;51(10):1253-8. doi: 10.1111/j.1365-4632.2012.05530.x.
Different types of laser have recently been reported as effective tools of treatment in striae distensae. Although fractional photothermolysis is effective for striae distensae, post-inflammatory hyperpigmentation is a major concern and common complication. There are no reports of the effects of using an intradermal radiofrequency (RF) device in striae distensae. Autologous platelet-rich plasma (PRP) is an effective treatment known for its wound-healing effects.
Nineteen Asian female patients with striae distensae were enrolled in this study. Three sessions of intradermal RF (1134-kHz frequency, 12-W power, 26-G electrode size) combined with autologous PRP were performed in each patient at intervals of four weeks. Patients were evaluated subjectively by the investigators and by themselves.
Evaluation of clinical results at four weeks after treatment showed that only one (5.3%) of the 19 patients achieved excellent improvement, whereas seven (36.8%) demonstrated marked improvement, six (31.6%) showed moderate improvement, and five (26.3%) showed mild improvement. None of the patients showed worsening of striae distensae. A total of 63.2% of patients reported they were "satisfied" or "very satisfied" with the degree of overall improvement.
Intradermal RF combined with autologous PRP appears to be an effective treatment for striae distensae.
不同类型的激光最近被报道为治疗膨胀纹的有效工具。虽然分 1 光热解对膨胀纹有效，但炎症后色素沉着过度是一个主要问题和常见并发症。目前尚无关于真皮内射频（RF）设备治疗膨胀纹效果的报道。自体富血小板血浆（PRP）是一种有效的治疗方法，以其促进伤口愈合的作用而闻名。
本研究纳入了 19 名患有膨胀纹的亚洲女性患者。每位患者在 4 周的间隔内接受 3 次真皮内 RF（1134-kHz 频率，12-W 功率，26-G 电极尺寸）联合自体 PRP 治疗。由研究者和患者自身对患者进行主观评估。
治疗后 4 周的临床结果评估显示，19 名患者中只有 1 名（5.3%）达到了优秀的改善效果，7 名（36.8%）患者表现出明显改善，6 名（31.6%）患者表现出中度改善，5 名（26.3%）患者表现出轻度改善。没有患者的膨胀纹出现恶化。共有 63.2%的患者报告他们对整体改善程度“满意”或“非常满意”。
真皮内 RF 联合自体 PRP 似乎是治疗膨胀纹的有效方法。
