Dermatology and Venereology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Pathology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
J Cosmet Dermatol. 2019 Jun;18(3):788-797. doi: 10.1111/jocd.12685. Epub 2018 Jun 19.
Striae distensae are very common cutaneous disorders that produce great psychological stress for women.
measure and compare between efficacy and tolerability of three modalities for treatment of striae distensae.
Forty-five female patients with striae distensae were randomly selected from the outpatient dermatology clinics of Al-Zahra university Hospital within 6 months period. Patients divided into three groups according to the therapeutic modalities were used. Group A: treated with carboxytherapy using carbon dioxide (CO2) injection, Group B: where patients were treated with intradermal injection of autologous platelet-rich plasma (PRP), and Group C: where we used tripolar radiofrequency (RF) for treatment.
All treated groups showed overall clinical improvement as regards the width, texture, and overall improvement after treatment (P > .05), with no statistically significant differences between the three groups. Patient's satisfaction was statistically significantly better in both group C (93.33%) and group A (80%) while group B (53.33%) was less with minimal side effects such as pain and ecchymosis, which were more frequent in group B than the other two groups; but with no statistically significance differences both groups A and C were effective with no significant differences in both types of striae and in any site of the body but group B is significantly more effective on striae rubra on trunk, with better improvement of lesions texture.
The three modalities of treatments proved to be effective clinically and histopathologically in treating both types of striae, which were well tolerated by the patients with minimal, transient side effects and our study results gave us guidelines for their clinical application.
妊娠纹是一种非常常见的皮肤疾病，会给女性带来很大的心理压力。
比较三种治疗方法治疗妊娠纹的疗效和耐受性。
在 6 个月的时间内，从 Al-Zahra 大学医院的皮肤科门诊随机选择了 45 名患有妊娠纹的女性患者。根据治疗方法将患者分为三组。A 组：采用二氧化碳（CO2）注射进行羧基疗法；B 组：患者接受自体富血小板血浆（PRP）皮内注射；C 组：采用三极射频（RF）进行治疗。
所有治疗组在治疗后宽度、质地和整体改善方面均显示出总体临床改善（P >.05），三组之间无统计学差异。C 组（93.33%）和 A 组（80%）的患者满意度均显著优于 B 组（53.33%），且副作用最小，如疼痛和瘀斑，B 组比其他两组更常见；但 A 组和 C 组均有效，两组在两种类型的妊娠纹和身体任何部位的疗效均无显著差异，但 B 组对躯干的红色妊娠纹更有效，病变质地改善更好。
三种治疗方法在治疗两种类型的妊娠纹方面均具有临床和组织病理学疗效，且患者耐受性良好，副作用轻微且短暂。我们的研究结果为它们的临床应用提供了指导。
