双模式成像及光激活纳米探针用于细胞的可控示踪
Dual imaging and photoactivated nanoprobe for controlled cell tracking.
机构信息
Center for Systems Biology, Massachusetts General Hospital/Harvard, Medical School, Boston, MA 02114, USA.
出版信息
Small. 2013 Jan 28;9(2):222-7. doi: 10.1002/smll.201201007. Epub 2012 Sep 21.
Abstract
A photoactivated nanoprobe for cell labeling and tracking is demonstrated. The nanoprobe enables all targeted cells to be imaged (at 680 nm) as well as specific cells to be photoactivated using 405 nm light. Photoactivated cells can then be tracked (at 525 nm) spatiotemporally in a separate channel over prolonged periods.
摘要
本文展示了一种用于细胞标记和示踪的光激活纳米探针。该纳米探针能够对所有靶向细胞进行成像（在 680nm 处），并使用 405nm 光对特定细胞进行光激活。然后，被光激活的细胞可以在一个单独的通道中被长时间、时空分辨地追踪（在 525nm 处）。
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