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Does endurance training protect from lipotoxicity?

作者信息

Roden Michael

机构信息

Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich-Heine University, Düsseldorf, Germany.

出版信息

Diabetes. 2012 Oct;61(10):2397-9. doi: 10.2337/db12-0662.

DOI:10.2337/db12-0662
PMID:22997429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3447918/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8a/3447918/0ac6ded2d150/2397fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8a/3447918/0ac6ded2d150/2397fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa8a/3447918/0ac6ded2d150/2397fig1.jpg

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本文引用的文献

1
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Diabetes. 2012 Oct;61(10):2472-8. doi: 10.2337/db11-1832. Epub 2012 Jul 10.
2
Mechanisms for insulin resistance: common threads and missing links.胰岛素抵抗的机制：共同线索和缺失环节。
Cell. 2012 Mar 2;148(5):852-71. doi: 10.1016/j.cell.2012.02.017.
3
Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans.骨骼肌二酰基甘油的定位和组成可预测人体的胰岛素抵抗。
Chronic Olanzapine Treatment Induces Disorders of Plasma Fatty Acid Profile in Balb/c Mice: A Potential Mechanism for Olanzapine-Induced Insulin Resistance.
慢性奥氮平治疗诱导Balb/c小鼠血浆脂肪酸谱紊乱：奥氮平诱导胰岛素抵抗的潜在机制
PLoS One. 2016 Dec 14;11(12):e0167930. doi: 10.1371/journal.pone.0167930. eCollection 2016.
4
Differences in the serum nonesterified Fatty Acid profile of young women associated with a recent history of gestational diabetes and overweight/obesity.近期有妊娠期糖尿病病史及超重/肥胖的年轻女性血清非酯化脂肪酸谱的差异。
PLoS One. 2015 May 26;10(5):e0128001. doi: 10.1371/journal.pone.0128001. eCollection 2015.
Diabetologia. 2012 Apr;55(4):1140-50. doi: 10.1007/s00125-011-2419-7. Epub 2012 Jan 15.
4
Enhanced fatty acid oxidation and FATP4 protein expression after endurance exercise training in human skeletal muscle.耐力运动训练后人体骨骼肌中脂肪酸氧化增强和 FATP4 蛋白表达增加。
PLoS One. 2012;7(1):e29391. doi: 10.1371/journal.pone.0029391. Epub 2012 Jan 3.
5
Executive summary: Standards of medical care in diabetes--2012.执行摘要：2012年糖尿病医疗护理标准
Diabetes Care. 2012 Jan;35 Suppl 1(Suppl 1):S4-S10. doi: 10.2337/dc12-s004.
6
Skeletal muscle triglycerides, diacylglycerols, and ceramides in insulin resistance: another paradox in endurance-trained athletes?胰岛素抵抗患者骨骼肌中的甘油三酯、二酰基甘油和神经酰胺：耐力训练运动员的另一个悖论？
Diabetes. 2011 Oct;60(10):2588-97. doi: 10.2337/db10-1221. Epub 2011 Aug 26.
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Increased intramuscular lipid synthesis and low saturation relate to insulin sensitivity in endurance-trained athletes.耐力训练运动员的肌肉内脂质合成增加和低饱和度与胰岛素敏感性有关。
J Appl Physiol (1985). 2010 May;108(5):1134-41. doi: 10.1152/japplphysiol.00684.2009. Epub 2010 Mar 18.
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Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle.脂质可用性增加会损害人体骨骼肌中胰岛素刺激的ATP合成。
Diabetes. 2006 Jan;55(1):136-40.