Onyango Agatha Christine, Walingo Mary Khakoni, Mbagaya Grace, Kakai Rose
Department of Nutrition and Health, School of Public Health and Community Development, Maseno University, Private Bag-40100 Maseno, Kenya.
J Nutr Metab. 2012;2012:306530. doi: 10.1155/2012/306530. Epub 2012 Sep 11.
Background. Nutritional status is an important determinant of HIV outcomes. Objective. To assess the nutrient intake and nutrient status of HIV seropositive patients attending an AIDS outpatient clinic, to improve the nutritional management of HIV-infected patients. Design. Prospective cohort study. Setting. Comprehensive care clinic in Chulaimbo Sub-District Hospital, Kenya. Subjects. 497 HIV sero-positive adults attending the clinic. Main Outcome Measures. Evaluation of nutrient intake using 24-hour recall, food frequency checklist, and nutrient status using biochemical assessment indicators (haemoglobin, creatinine, serum glutamate pyruvate (SGPT) and mean corpuscular volume (MCV)). Results. Among the 497 patients recruited (M : F sex ratio: 1.4, mean age: 39 years ± 10.5 y), Generally there was inadequate nutrient intake reported among the HIV patients, except iron (10.49 ± 3.49 mg). All the biochemical assessment indicators were within normal range except for haemoglobin 11.2 g/dL (11.4 ± 2.60 male and 11.2 ± 4.25 female). Conclusions. Given its high frequency, malnutrition should be prevented, detected, monitored, and treated from the early stages of HIV infection among patients attending AIDS clinics in order to improve survival and quality of life.
背景。营养状况是影响艾滋病预后的重要因素。目的。评估在艾滋病门诊就诊的HIV血清阳性患者的营养摄入和营养状况，以改善对HIV感染患者的营养管理。设计。前瞻性队列研究。地点。肯尼亚Chulaimbo地区医院的综合护理诊所。研究对象。497名在该诊所就诊的HIV血清阳性成年人。主要观察指标。使用24小时回顾法、食物频率清单评估营养摄入情况，并使用生化评估指标（血红蛋白、肌酐、血清谷丙转氨酶（SGPT）和平均红细胞体积（MCV））评估营养状况。结果。在招募的497名患者中（男女比例为1.4，平均年龄：39岁±10.5岁），除铁（10.49±3.49毫克）外，HIV患者普遍存在营养摄入不足的情况。除血红蛋白为11.2克/分升（男性为11.4±2.60，女性为11.2±4.25）外，所有生化评估指标均在正常范围内。结论。鉴于营养不良的发生率较高，应在艾滋病诊所就诊的患者中，从HIV感染的早期阶段就对营养不良进行预防、检测、监测和治疗，以提高生存率和生活质量。
