人乳头多瘤空泡病毒BKV的基因组。
The genome of human papovavirus BKV.
作者信息
Seif I, Khoury G, Dhar R
出版信息
Cell. 1979 Dec;18(4):963-77. doi: 10.1016/0092-8674(79)90209-5.
The complete DNA sequence of human papovavirus BKV(Dun), consisting of 5153 nucleotide pairs, is presented. We describe the segments of the genome which correspond to the replication origin, the tandem repeated sequences, the 5' and 3' ends of the mRNAs, the splice sites, the early and late viral proteins and the putative viral polypeptides. These BKV DNA sequences are compared with analogous regions in the SV40 and Py virus genomes in an attempt to localize viral functions for lytic growth and transformation.
本文给出了人乳头多瘤空泡病毒BKV（Dun）由5153个核苷酸对组成的完整DNA序列。我们描述了基因组中与复制起点、串联重复序列、mRNA的5'和3'末端、剪接位点、早期和晚期病毒蛋白以及推定的病毒多肽相对应的片段。将这些BKV DNA序列与SV40和Py病毒基因组中的类似区域进行比较，试图定位病毒裂解生长和转化的功能。
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