Kanda T, Yoshiike K, Takemoto K K
J Virol. 1983 Apr;46(1):333-6. doi: 10.1128/JVI.46.1.333-336.1983.
We located the origin of DNA replication of African green monkey B-lymphotropic papovavirus DNA by analyzing pulse-labeled form I DNA. With the replication origin used as a reference point, the B-lymphotropic papovavirus genome was aligned with the genomes of simian virus 40 and BK virus from DNA homology between specific fragments hybridized under low-stringency conditions. From the results of these experiments, it was possible to deduce the correlation between the physical and functional maps of the B-lymphotropic papovavirus genome.
我们通过分析脉冲标记的I型DNA来定位非洲绿猴嗜B淋巴细胞乳头瘤病毒DNA的复制起点。以复制起点作为参考点，根据在低严格条件下杂交的特定片段之间的DNA同源性，将嗜B淋巴细胞乳头瘤病毒基因组与猴病毒40和BK病毒的基因组进行比对。从这些实验结果中，可以推断出嗜B淋巴细胞乳头瘤病毒基因组物理图谱和功能图谱之间的相关性。
