Larrea Maria Rupérez, Carreño Maria Cristina, Fine Paul E M
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Lepr Rev. 2012 Jun;83(2):184-94.
Data from the Mexican national leprosy control programme 1989-2009 are described and analysed. After initial increases associated with the introduction of MDT and the start of the global elimination initiative in the early 1990 s, both prevalence and incidence declined dramatically throughout most of the country. Reported prevalence fell below 1 per 10000 in 1994 and has remained below that level ever since. There is considerable geographic heterogeneity, with highest case detection rates in western states bordering the Pacific and lowest in the south east. Reasons for these geographic differences are unclear. There is evidence of increases in average age of cases, and in proportions male and MB, as in several other populations with declining leprosy. There is some evidence of increasing leprosy in states bordering on Texas, USA, where M. leprae is known to be harboured in armadillos. The relevance of armadillos for leprosy in Mexico is unclear but a priority question.
对1989 - 2009年墨西哥国家麻风病控制项目的数据进行了描述和分析。在20世纪90年代初随着多药疗法的引入以及全球消除麻风病倡议的启动而出现最初的增长之后，该国大部分地区的患病率和发病率都急剧下降。报告的患病率在1994年降至每万人1例以下，此后一直维持在该水平以下。存在相当大的地理差异，与太平洋接壤的西部各州病例发现率最高，而东南部最低。这些地理差异的原因尚不清楚。有证据表明病例的平均年龄增加，男性和多菌型病例的比例增加，这与其他麻风病发病率下降的人群情况相同。有一些证据表明，在美国得克萨斯州接壤的各州麻风病有所增加，已知犰狳携带麻风杆菌。犰狳在墨西哥麻风病中的作用尚不清楚，但这是一个优先问题。
