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新发病例中老年人和儿童的麻风病——一项3年回顾性研究

Leprosy in Elderly and Children among New Cases - A 3-Year Retrospective Study.

作者信息

Arunraghav Potharaju, Herakal Kallappa

机构信息

Department of Dermatology, Deccan Medical College, Hyderabad, Telangana, India.

Department of Dermatology, Navodaya Medical College, Raichur, Karnataka, India.

出版信息

Indian Dermatol Online J. 2021 Mar 2;12(2):294-297. doi: 10.4103/idoj.IDOJ_177_18. eCollection 2021 Mar-Apr.

DOI:10.4103/idoj.IDOJ_177_18
PMID:33959528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8088175/
Abstract

BACKGROUND

Leprosy occurs in all age groups, with adults constituting the majority. However, leprosy in children always drew the attention of epidemiologists as a guide to transmission of leprosy. With increasing life expectancy and decreasing prevalence of leprosy, there is going to be a significant rise of leprosy among elderly in India. In elderly leprosy patients, clinical signs are often quiet, which makes it a hidden source of infection. The detection of leprosy in elderly is of epidemiological importance, hence it is critical that due attention be given to leprosy in elderly as a possible contributor to hidden leprosy in India.

AIM

To analyze leprosy in elderly and in children from the records of new patients seen over the past 3-year period.

METHODS

Analysis of details of "leprosy in elderly" and "leprosy in children'" from the records of new leprosy patients seen at a dermatology OPD of a teaching hospital over a period of 3 years.

RESULTS

Out of 157 patients, 34 (21.6%) were above 45 years, while 18 (11.4%) were below 15 years, the difference being statistically significant ( > 0.05). Bacteriological Index (BI) values in elderly were higher compared to children. In addition, elderly had a higher percentage of multibacillary (MB) leprosy compared to children both clinically (35% vs 22%) and histopathologically (38% vs 22%).

CONCLUSION

Leprosy in elderly is an important entity, and there is a need to study it as a distinct group. It will provide information on hidden leprosy load and apprise us on sources of infection in the community.

摘要

背景

麻风病可见于所有年龄组,其中成年人占大多数。然而,儿童麻风病一直吸引着流行病学家的关注,将其作为麻风病传播的一个指标。随着预期寿命的增加和麻风病患病率的下降,印度老年人中的麻风病病例预计将显著增加。在老年麻风病患者中,临床症状往往不明显,这使其成为一个潜在的传染源。老年麻风病的检测具有重要的流行病学意义,因此,必须高度重视印度老年人群中的麻风病,因为它可能是隐匿性麻风病的一个来源。

目的

通过分析过去3年新确诊患者的记录,研究老年和儿童麻风病的情况。

方法

分析一家教学医院皮肤科门诊3年来新确诊麻风病患者记录中的“老年麻风病”和“儿童麻风病”的详细信息。

结果

157例患者中,34例(21.6%)年龄在45岁以上,18例(11.4%)年龄在15岁以下,差异具有统计学意义(P>0.05)。老年患者的细菌学指数(BI)值高于儿童。此外,无论是临床诊断(35%对22%)还是组织病理学诊断(38%对22%),老年多菌型(MB)麻风病患者的比例均高于儿童。

结论

老年麻风病是一个重要的研究对象,有必要将其作为一个独立的群体进行研究。这将为隐匿性麻风病负担提供信息,并使我们了解社区中的传染源。

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