Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Diabet Med. 2013 Mar;30(3):326-32. doi: 10.1111/dme.12013.
To describe the burden of diabetes mellitus and impaired fasting glucose in middle-aged residents (35-64 years) in an urban area of Sri Lanka.
A cross-sectional survey was conducted in the Ragama Medical Officer of Health area, from which 2986 participants (1349 men and 1637 women) were randomly selected from the electoral registry between January and December 2007. The participants underwent a physical examination and had their height, weight, waist and hip circumferences and blood pressure measured by trained personnel. Fasting blood samples were taken for measurement of glucose, HbA(1c) and lipids. The prevalence of diabetes (fasting plasma glucose > 7 mmol/l) and impaired fasting glycaemia (fasting plasma glucose 5.6-6.9 mmol/l) and major predictors of diabetes in Sri Lanka were estimated from the population-based data.
Age-adjusted prevalence of diabetes mellitus in this urban population was 20.3% in men and 19.8% in women. Through the present screening, 263 patients with diabetes and 1262 with impaired fasting glucose levels were identified. The prevalence of newly detected diabetes was 35.7% of all patients with diabetes. Among patients with diabetes, only 23.8% were optimally controlled. In the regression models, high BMI, high waist circumference, high blood pressure and hypercholesterolaemia increased the fasting plasma glucose concentration, independent of age, sex and a family history of diabetes.
Our data demonstrate the heavy burden of diabetes in this urban population. Short- and long-term control strategies are required, not only for optimal therapy among those affected, but also for nationwide primary prevention of diabetes.
描述斯里兰卡一个城市中年居民（35-64 岁）糖尿病和空腹血糖受损的负担。
在拉嘎马医疗官辖区进行了一项横断面调查，从 2007 年 1 月至 12 月期间从选举登记册中随机选择了 2986 名参与者（1349 名男性和 1637 名女性）。参与者接受了体检，并由经过培训的人员测量了他们的身高、体重、腰围和臀围以及血压。采集空腹血样测量血糖、HbA（1c）和血脂。根据基于人群的数据，估算了糖尿病（空腹血糖>7mmol/l）和空腹血糖受损（空腹血糖 5.6-6.9mmol/l）在斯里兰卡的流行率以及糖尿病的主要预测因素。
该城市人群中，年龄校正后的糖尿病患病率为男性 20.3%，女性 19.8%。通过本次筛查，发现 263 例糖尿病患者和 1262 例空腹血糖受损患者。新发糖尿病的患病率占所有糖尿病患者的 35.7%。在糖尿病患者中，仅有 23.8%的患者得到了最佳控制。在回归模型中，高 BMI、高腰围、高血压和高胆固醇血症均使空腹血糖浓度升高，与年龄、性别和糖尿病家族史无关。
我们的数据表明，这种城市人群中糖尿病的负担很重。不仅需要对受影响者进行短期和长期的控制策略，还需要在全国范围内进行糖尿病的初级预防。
