Cheung Winston, Clayton Nicola, Li Frank, Tan Jeff, Milliss David, Thanakrishnan Govindasamy, Maitz Peter
Concord Repatriation General Hospital, Sydney, NSW, Australia.
Int J Speech Lang Pathol. 2013 Apr;15(2):216-20. doi: 10.3109/17549507.2012.713396. Epub 2012 Sep 24.
The objective of this study was to determine if intubation using larger endotracheal tube sizes in mechanically ventilated patients with thermal burn injury adversely affects voice and swallowing function. This prospective, observational study was conducted in patients with thermal burn injuries, who were mechanically ventilated via an endotracheal tube. The primary outcome measures were changes in voice and swallowing function, assessed using the Australian Therapy Outcome Measures (AusTOMS), immediately before the burn injury, and 12 months after the removal of the endotracheal tube. Of 101 patients screened, 20 male patients were followed for 12 months. Patients intubated with size 8.0 or larger endotracheal tubes were compared to patients with size 7.5 endotracheal tubes or smaller. Patients with the larger endotracheal tubes had a significant 1.8-point (9%) decline in their AusTOMS voice score (p =.01) using the paired t-test, but there was no significant difference between the two groups using the independent samples t-test. There was no significant difference in swallowing outcome between the two groups. Male patients with thermal burn injuries, mechanically ventilated using size 8.0 endotracheal tubes or larger, had a statistically significant decline in voice outcome; however, interpretation of this result is limited by methodological considerations.
本研究的目的是确定在机械通气的热烧伤患者中使用更大尺寸的气管内导管进行插管是否会对声音和吞咽功能产生不利影响。这项前瞻性观察性研究在通过气管内导管进行机械通气的热烧伤患者中进行。主要结局指标是在烧伤前以及拔除气管内导管12个月后,使用澳大利亚治疗结局测量量表(AusTOMS)评估的声音和吞咽功能变化。在筛查的101例患者中,20例男性患者被随访了12个月。将使用8.0号或更大尺寸气管内导管插管的患者与使用7.5号或更小尺寸气管内导管的患者进行比较。使用配对t检验,使用较大尺寸气管内导管的患者的AusTOMS声音评分显著下降了1.8分(9%)(p = 0.01),但使用独立样本t检验时两组之间没有显著差异。两组之间的吞咽结局没有显著差异。使用8.0号或更大尺寸气管内导管进行机械通气的男性热烧伤患者的声音结局有统计学意义的下降;然而,该结果的解释受到方法学考虑因素的限制。