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母婴 HIV 健康状况的影响:父母与孩子共同应对项目中 12 年儿童的研究。

Impact of maternal HIV health: a 12-year study of children in the Parents And Children Coping Together project.

机构信息

Department of Psychiatry, Health Risk Reduction Projects, Integrated Substance Abuse Programs, University of California, Los Angeles, California 90025, USA.

出版信息

J Adolesc Health. 2012 Oct;51(4):313-8. doi: 10.1016/j.jadohealth.2011.12.025. Epub 2012 Mar 3.

Abstract

PURPOSE

The purpose of this 12-year longitudinal study was to assess the effects of maternal HIV/AIDS on child/adolescent well-being and behavioral outcomes, extending an earlier published account.

METHODS

Interviews were conducted with 66 pairs of healthy children and their mothers living with HIV/AIDS, who are participants in the Parents And children Coping Together (PACT) project begun in 1997. All study participants were English or Spanish speaking. About half (48.5%) of the youth were female. Maternal health status (e.g., viral load biomedical marker, illness symptoms, physical functioning, and depression) and child/adolescent outcomes (e.g., depression, anxiety/worry, aggression, and self-concept) were assessed over 16 time points.

RESULTS

Using growth curve modeling, results show a negative effect of maternal health status on child/adolescent outcomes, including child/adolescent depression, anxiety/worry, aggression, and self-concept. Interaction effects within the growth models suggest younger children are more impacted by poor maternal health than are older children/adolescents.

CONCLUSIONS

This is the first study to follow a cohort of children of mothers living with HIV/AIDS over such an extended age range, through late adolescence/early adulthood, to determine the impact of maternal health status throughout the entire developmental period.

摘要

目的

本为期 12 年的纵向研究旨在评估母婴 HIV/AIDS 对儿童/青少年健康和行为结果的影响,这是对早期已发表报告的扩展。

方法

本研究对 66 对健康的 HIV/AIDS 母婴进行了访谈,这些母婴是始于 1997 年的父母与子女共同应对(PACT)项目的参与者。所有研究参与者都说英语或西班牙语。大约一半(48.5%)的青少年为女性。在 16 个时间点评估了母婴健康状况(例如病毒载量生物标志物、疾病症状、身体机能和抑郁)和儿童/青少年结果(例如抑郁、焦虑/担忧、攻击和自我概念)。

结果

使用增长曲线模型,结果表明母婴健康状况对儿童/青少年结果(包括儿童/青少年抑郁、焦虑/担忧、攻击和自我概念)有负面影响。增长模型中的交互效应表明,与年龄较大的儿童/青少年相比,年幼的儿童受不良母婴健康的影响更大。

结论

这是第一项对母婴 HIV/AIDS 儿童进行如此长年龄段(从青春期晚期到成年早期)的队列研究,以确定母婴健康状况对整个发育阶段的影响。

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