Department of Psychiatry, Health Risk Reduction Projects, Integrated Substance Abuse Programs, University of California, Los Angeles, California 90025, USA.
J Adolesc Health. 2012 Oct;51(4):313-8. doi: 10.1016/j.jadohealth.2011.12.025. Epub 2012 Mar 3.
The purpose of this 12-year longitudinal study was to assess the effects of maternal HIV/AIDS on child/adolescent well-being and behavioral outcomes, extending an earlier published account.
Interviews were conducted with 66 pairs of healthy children and their mothers living with HIV/AIDS, who are participants in the Parents And children Coping Together (PACT) project begun in 1997. All study participants were English or Spanish speaking. About half (48.5%) of the youth were female. Maternal health status (e.g., viral load biomedical marker, illness symptoms, physical functioning, and depression) and child/adolescent outcomes (e.g., depression, anxiety/worry, aggression, and self-concept) were assessed over 16 time points.
Using growth curve modeling, results show a negative effect of maternal health status on child/adolescent outcomes, including child/adolescent depression, anxiety/worry, aggression, and self-concept. Interaction effects within the growth models suggest younger children are more impacted by poor maternal health than are older children/adolescents.
This is the first study to follow a cohort of children of mothers living with HIV/AIDS over such an extended age range, through late adolescence/early adulthood, to determine the impact of maternal health status throughout the entire developmental period.
本为期 12 年的纵向研究旨在评估母婴 HIV/AIDS 对儿童/青少年健康和行为结果的影响,这是对早期已发表报告的扩展。
本研究对 66 对健康的 HIV/AIDS 母婴进行了访谈,这些母婴是始于 1997 年的父母与子女共同应对(PACT)项目的参与者。所有研究参与者都说英语或西班牙语。大约一半(48.5%)的青少年为女性。在 16 个时间点评估了母婴健康状况(例如病毒载量生物标志物、疾病症状、身体机能和抑郁)和儿童/青少年结果(例如抑郁、焦虑/担忧、攻击和自我概念)。
使用增长曲线模型,结果表明母婴健康状况对儿童/青少年结果(包括儿童/青少年抑郁、焦虑/担忧、攻击和自我概念)有负面影响。增长模型中的交互效应表明,与年龄较大的儿童/青少年相比,年幼的儿童受不良母婴健康的影响更大。
这是第一项对母婴 HIV/AIDS 儿童进行如此长年龄段(从青春期晚期到成年早期)的队列研究,以确定母婴健康状况对整个发育阶段的影响。