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一种治疗敏感牙齿的新方法:脱敏漱口液。

A new treatment alternative for sensitive teeth: a desensitizing oral rinse.

机构信息

Department of Oral Biology, New Jersey Dental School, University of Medicine and Dentistry of New Jersey, 185 South Orange Ave, Newark, NJ 07103, USA.

出版信息

J Dent. 2013 Mar;41 Suppl 1:S1-11. doi: 10.1016/j.jdent.2012.09.007. Epub 2012 Sep 19.

Abstract

OBJECTIVE

Tooth sensitivity is a common, painful dental condition. Consumer dental products, mostly dentifrices, play an important role in sensitivity treatment. The objective of this review is to describe a new mouthwash-based desensitizing technology.

DATA

Background literature concerning desensitizing products is reviewed. Potassium salts are the most commonly used active ingredients in desensitizing dentifrices. Clinical studies show that while potassium salt dentifrices are generally effective; most formulations require several weeks to exert their desensitizing effect. Recently, a new desensitizing dentifrice containing the amino acid arginine was introduced. This dentifrice acts to occlude the dentinal tubules, and has been shown to be highly effective in multiple clinical studies. This arginine-containing dentifrice has also been shown to provide instant relief of sensitivity pain when applied directly to the sensitive tooth surface. In contrast to dentifrices, there are few desensitizing mouthwashes available. Building on the success of the arginine-based dentifrice, an arginine-based mouthwash formula was developed and tested.

SOURCES

Published studies in peer-reviewed publications.

STUDY SELECTION

Controlled and blinded clinical studies to provide evidence of efficacy. In vitro studies are included to indicate the mechanism of action. This review includes studies testing the new arginine-based desensitizing mouthwash.

CONCLUSION

Clinical findings indicate that this new desensitizing mouthwash, based on the Pro-Argin™ mouthwash technology effectively reduces sensitivity symptoms and can be used alone or as a adjunct to the use of the arginine-containing dentifrice in the home treatment of tooth sensitivity.

摘要

目的

牙齿敏感是一种常见的、疼痛的牙齿状况。消费者口腔护理产品(主要是牙膏)在敏感性治疗中起着重要作用。本综述的目的是描述一种基于漱口剂的新型脱敏技术。

资料

综述了有关脱敏产品的背景文献。钾盐是脱敏牙膏中最常用的活性成分。临床研究表明,虽然钾盐牙膏通常有效,但大多数配方需要数周时间才能发挥其脱敏作用。最近,一种含有氨基酸精氨酸的新型脱敏牙膏被推出。这种牙膏的作用是封闭牙本质小管,多项临床研究表明其效果非常显著。在直接应用于敏感牙齿表面时,这种含精氨酸的牙膏也能立即缓解敏感性疼痛。与牙膏相比,可用的脱敏漱口水寥寥无几。在精氨酸牙膏成功的基础上,开发并测试了一种基于精氨酸的漱口水配方。

来源

同行评审出版物中已发表的研究。

研究选择

为提供疗效证据而进行的对照和盲法临床试验。包括体外研究以表明作用机制。本综述包括测试新型基于精氨酸的脱敏漱口水的研究。

结论

临床研究结果表明,这种基于 Pro-ArginTM 漱口水技术的新型脱敏漱口水可有效减轻敏感性症状,可单独使用,也可与含精氨酸的牙膏联合使用,在家中治疗牙齿敏感。

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