避孕套预防非病毒性性传播感染的效果：一项使用电子日常日记的前瞻性研究。
Condom effectiveness against non-viral sexually transmitted infections: a prospective study using electronic daily diaries.
机构信息
Department of Health Behavior, College of Public Health at the University of Kentucky, 151 Washington Avenue, Lexington, KY 40506-0003, USA.
出版信息
Sex Transm Infect. 2012 Nov;88(7):484-9. doi: 10.1136/sextrans-2012-050618. Epub 2012 Sep 21.
OBJECTIVES
To prospectively evaluate the protective value of consistent and correct use of latex condoms against the acquisition of Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis.
METHODS
Patients (N=929) attending clinics that treat sexually transmitted infections (STIs) were prospectively followed for up to 6 months. Urine STI nucleic acid amplification testing was performed at baseline, 3 months and 6 months. Participants were instructed to respond to daily prompts from a handheld device by completing a report for each penile-vaginal sexual intercourse event. Generalised estimating equation models examined associations of consistent as well as consistent and correct condom use with STI incidence over 3-month intervals.
RESULTS
Consistent condom use was not significantly associated with STI incidence (Estimated OR (EOR)=0.75; 95% CI (CI) 0.43 to 1.30; p=0.31). However, individuals who used condoms both correctly and consistently were estimated to have 59% lower odds of acquiring an STI (EOR=0.41; 95% CI 0.19 to 0.90; p=.026), compared to those who did not.
CONCLUSIONS
The correct as well as the consistent use of condoms greatly reduces the odds of non-viral STI acquisition.
目的
前瞻性评估坚持正确使用乳胶安全套对预防沙眼衣原体、淋病奈瑟菌和阴道毛滴虫感染的保护作用。
方法
本研究前瞻性随访了 929 名就诊于性传播感染（STI）门诊的患者，随访时间最长达 6 个月。基线、3 个月和 6 个月时进行尿液 STI 核酸扩增检测。参与者被要求通过手持设备对每日提示做出回应，完成每次阴茎阴道性交事件的报告。广义估计方程模型分析了坚持使用以及坚持正确使用安全套与 3 个月间隔内 STI 发生率之间的关联。
结果
坚持使用安全套与 STI 发病率无显著相关性（估计比值比[OR] = 0.75；95%置信区间[CI] 0.43 至 1.30；p=0.31）。然而，与未坚持正确使用安全套者相比，坚持正确使用安全套者感染 STI 的几率估计降低了 59%（OR=0.41；95% CI 0.19 至 0.90；p=0.026）。
结论
正确且坚持使用安全套可大大降低非病毒性 STI 的感染风险。
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