Berezney R, Basler J, Kaplan S C, Hughes B B
Eur J Cell Biol. 1979 Dec;20(2):139-42.
The nuclear matrix of slowly proliferating rat liver is compared with rapidly proliferating regenerating liver and Zajdela ascites hepatoma cells. While no differences are detected in overall ultrastructure, composition or polypeptide profiles of normal liver versus regenerating liver matrices, significant alterations are observed in the polypeptides of Zajdela hepatoma nuclear matrices.
将缓慢增殖的大鼠肝脏的核基质与快速增殖的再生肝脏及扎伊德拉腹水肝癌细胞的核基质进行比较。虽然正常肝脏与再生肝脏基质在整体超微结构、组成或多肽谱方面未检测到差异,但在扎伊德拉肝癌细胞核基质的多肽中观察到了显著变化。