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牙龈浆母细胞淋巴瘤误诊为反应性病变：一例报告

Plasmablastic lymphoma of gingiva mimicking a reactive lesion: a case report.

作者信息

Bagul Neeta, Mamatha G S, Mahalle Aditi

机构信息

Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Pimpri, Pune 411018, India.

出版信息

Case Rep Dent. 2012;2012:259307. doi: 10.1155/2012/259307. Epub 2012 Sep 13.

DOI:10.1155/2012/259307
PMID:23008784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3449107/
Abstract

Oral plasmablastic lymphoma (PBL) is a rare malignancy, associated with HIV or other immunocompromised conditions. The lesion constituted a new subtype of diffuse large B-cell lymphoma and proposed a distinct entity based on its basic morphology, its clinical behaviour involving predominantly extramedullary sites (particularly oral cavity), and its limited antigenic phenotype data suggesting plasmacytic differentiation. Authors here report a case of apparently healthy individual aged 35 years, presenting one-month history of swelling associated with loosened teeth around upper anteriors. Following incisional biopsy, routine histopathologic and immunohistochemical studies, the diagnosis of plasmablastic lymphoma was given.

摘要

口腔浆母细胞性淋巴瘤（PBL）是一种罕见的恶性肿瘤，与HIV或其他免疫功能低下的情况相关。该病变构成了弥漫性大B细胞淋巴瘤的一种新亚型，并基于其基本形态、主要累及髓外部位（尤其是口腔）的临床行为以及提示浆细胞分化的有限抗原表型数据提出了一个独特的实体。本文作者报告了一例35岁看似健康的个体，有一个月的上前牙周围肿胀伴牙齿松动的病史。经切开活检、常规组织病理学和免疫组织化学研究后，诊断为浆母细胞性淋巴瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/0dea8d4a1297/CRIM.DENTISTRY2012-259307.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/49aeff3e8f76/CRIM.DENTISTRY2012-259307.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/4f1953e00ca6/CRIM.DENTISTRY2012-259307.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/cfcf1da44ef9/CRIM.DENTISTRY2012-259307.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/0dea8d4a1297/CRIM.DENTISTRY2012-259307.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/49aeff3e8f76/CRIM.DENTISTRY2012-259307.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/4f1953e00ca6/CRIM.DENTISTRY2012-259307.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/cfcf1da44ef9/CRIM.DENTISTRY2012-259307.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63f8/3449107/0dea8d4a1297/CRIM.DENTISTRY2012-259307.004.jpg

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Plasmablastic lymphoma: a review.浆母细胞淋巴瘤综述
免疫功能正常个体的浆母细胞淋巴瘤中与治疗相关的并发症。
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