Department of Dermatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Australas J Dermatol. 2013 Nov;54(4):277-82. doi: 10.1111/j.1440-0960.2012.00939.x. Epub 2012 Aug 17.
Plasmablastic lymphoma (PBL) is a recently described rare variant of diffuse large B-cell lymphoma characterised by its aggressive nature and plasmacytic differentiation. It most frequently arises in the oral cavity of human immunodeficiency virus (HIV)-infected patients. However extra-oral involvement is becoming increasingly recognised, particularly in HIV-negative patients. We report a case of PBL presenting as multiple violaceous nodules and plaques on the leg of a HIV-negative patient, 13-years post-renal transplant. To date, 20 cases of PBL presenting in the skin have been reported. We review and compare the clinico-pathological features of these cases.
浆母细胞淋巴瘤（PBL）是一种新近描述的弥漫性大 B 细胞淋巴瘤的罕见变异型，其特征为侵袭性和浆细胞分化。它最常发生在人类免疫缺陷病毒（HIV）感染患者的口腔中。然而，越来越多的人认识到其也会发生在口腔以外的部位，尤其是在 HIV 阴性患者中。我们报告了一例 HIV 阴性患者肾移植 13 年后，腿部出现多发性紫红色结节和斑块的 PBL 病例。迄今为止，已有 20 例 PBL 病例在皮肤中出现。我们对这些病例的临床病理特征进行了回顾和比较。
