关于聚合物通过纳米孔的 Lubensky-Nelson 模型。
On the Lubensky-Nelson model of polymer translocation through nanopores.
机构信息
Universität Bielefeld, Fakultät für Physik, Bielefeld, Germany.
出版信息
Biophys J. 2012 Sep 5;103(5):889-97. doi: 10.1016/j.bpj.2012.07.036.
Abstract
We revisit the one-dimensional stochastic model of an earlier study by D. K. Lubensky and D. R. Nelson for the electrically driven translocation of polynucleotides through α-hemolysin pores. We show that the model correctly describes two further important properties of the experimentally observed translocation time distributions, namely their spread (width) and their exponential decay. The resulting overall agreement between theoretical and experimental translocation time distributions is thus very good.
摘要
我们重新研究了 D. K. Lubensky 和 D. R. Nelson 之前关于多核苷酸通过α-溶血素孔电驱动易位的一维随机模型。我们表明，该模型正确描述了实验观察到的易位时间分布的另外两个重要性质，即它们的分散度（宽度）和指数衰减。因此，理论和实验易位时间分布之间的总体一致性非常好。
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