Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shengyang 110016, People's Republic of China.
Fitoterapia. 2012 Dec;83(8):1636-42. doi: 10.1016/j.fitote.2012.09.015. Epub 2012 Sep 23.
Phytochemical analysis of the extract from the seed oil leavings of Xanthoceras sorbifolia Bunge led to the isolation of five new oleanane-type triterpeniod saponins, sorbifoliasides G-K (1-5). Their structures were elucidated on the basis of spectroscopic analysis and chemical derivatization. To our knowledge, compound 5 is the first example of a naturally occurring 3,28-O-bisdesmosic triterpenoid saponin with olefinic linkages at C12 and C15. The cytotoxicity of all compounds against ten selected human cancer cell lines was assayed.
从文冠果种子油渣的提取物中进行的植物化学分析导致分离出五种新的齐墩果烷型三萜皂苷，即 sorbifoliasides G-K（1-5）。基于光谱分析和化学衍生化，确定了它们的结构。据我们所知，化合物 5 是第一个在自然界中存在的具有 C12 和 C15 处双键的 3,28-O-双糖基三萜皂苷。对所有化合物对十种选定的人癌细胞系的细胞毒性进行了测定。
