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近期髋部骨折老年女性的椎体骨折评估:BREAK 研究。

The assessment of vertebral fractures in elderly women with recent hip fractures: the BREAK Study.

机构信息

Department of Internal Medicine, Endocrine-Metabolic Science and Biochemistry, University of Siena, Policlinico Le Scotte, Viale Bracci 2, 53100, Siena, Italy.

出版信息

Osteoporos Int. 2013 Apr;24(4):1151-9. doi: 10.1007/s00198-012-2119-2. Epub 2012 Aug 22.

Abstract

UNLABELLED

This study aimed to evaluate the prevalence of vertebral fractures in elderly women with a recent hip fracture. The burden of vertebral fractures expressed by the Spinal Deformity Index (SDI) is more strictly associated with the trochanteric than the cervical localization of hip fracture and may influence short-term functional outcomes.

INTRODUCTION

This study aimed to determine the prevalence and severity of vertebral fractures in elderly women with recent hip fracture and to assess whether the burden of vertebral fractures may be differently associated with trochanteric hip fractures with respect to cervical hip fractures.

METHODS

We studied 689 Italian women aged 60 years or over with a recent low trauma hip fracture and for whom an adequate X-ray evaluation of spine was available. All radiographs were examined centrally for the presence of any vertebral deformities and radiological morphometry was performed. The SDI, which integrates both the number and the severity of fractures, was also calculated.

RESULTS

Prevalent vertebral fractures were present in 55.7% of subjects and 95 women (13.7%) had at least one severe fracture. The women with trochanteric hip fracture showed higher SDI and higher prevalence of diabetes with respect to those with cervical hip fracture, p=0.017 and p=0.001, respectively. SDI, surgical menopause, family history of fragility fracture, and type2 diabetes mellitus were independently associated with the risk of trochanteric hip fracture. Moreover, a higher SDI was associated with a higher percentage of post-surgery complications (p=0.05) and slower recovery (p<0.05).

CONCLUSIONS

Our study suggests that the burden of prevalent vertebral fractures is more strictly associated with the trochanteric than the cervical localisation of hip fracture and that elevated values of SDI negatively influence short term functional outcomes in women with hip fracture.

摘要

目的

本研究旨在评估近期髋部骨折的老年女性中椎体骨折的发生率。脊柱畸形指数(SDI)所表示的椎体骨折负担与髋部骨折的转子间部位比颈部位更密切相关,并且可能会影响短期的功能结局。

引言

本研究旨在确定近期髋部骨折的老年女性中椎体骨折的发生率和严重程度,并评估椎体骨折负担是否与转子间髋部骨折相比,与颈髋部骨折的关系不同。

方法

我们研究了 689 名年龄在 60 岁或以上、有近期低创伤性髋部骨折且脊柱 X 线评估充分的意大利女性。所有 X 射线均由中心进行检查,以确定是否存在任何椎体畸形,并进行放射形态计量学检查。还计算了 SDI,该指数综合了骨折的数量和严重程度。

结果

55.7%的患者存在现患椎体骨折,95 名患者(13.7%)至少有一处严重骨折。与颈髋部骨折患者相比,转子间髋部骨折患者的 SDI 更高,且糖尿病的患病率更高(p=0.017 和 p=0.001)。SDI、手术绝经、脆性骨折家族史和 2 型糖尿病与转子间髋部骨折的风险独立相关。此外,SDI 越高,术后并发症的比例越高(p=0.05),恢复速度越慢(p<0.05)。

结论

我们的研究表明,现患椎体骨折的负担与髋部骨折的转子间部位比颈部位更密切相关,SDI 值升高会对髋部骨折女性的短期功能结局产生负面影响。

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