MMWR Morb Mortal Wkly Rep. 2012 Sep 28;61:764-7.
Since July 2012, 305 cases of infection with influenza A (H3N2) variant (H3N2v) virus containing the influenza A (H1N1)pdm09 M gene have occurred in multiple U.S. states, primarily associated with swine exposure at agricultural fairs. In Ohio, from July 28 to September 25, 2012, a total of 106 confirmed H3N2v cases were identified through enhanced surveillance. Whereas most H3N2v patients experienced mild, self-limited influenza-like illness (ILI), 11 of the Ohio patients were hospitalized, representing 69% of all H3N2v hospitalizations in the United States. Of these hospitalized H3N2v patients, six were at increased risk for influenza complications because of age or underlying medical conditions, including the only H3N2v-associated fatality reported in the United States to date. This report summarizes the epidemiology and clinical features of the 11 hospitalized H3N2v patients in Ohio. These findings reinforce the recommendation for persons at high risk for influenza complications to avoid swine exposure at agricultural fairs this fall. In addition, persons not at high risk for influenza complications who wish to reduce their risk for infection with influenza viruses circulating among pigs also should avoid swine and swine barns at agricultural fairs this fall.
自 2012 年 7 月以来，美国多个州共发生了 305 例感染甲型流感（H3N2）变异（H3N2v）病毒的病例，这些病例主要与农业展览会上的猪接触有关。在俄亥俄州，从 2012 年 7 月 28 日至 9 月 25 日，通过加强监测共发现了 106 例确诊的 H3N2v 病例。尽管大多数 H3N2v 患者出现了轻度、自限性流感样疾病（ILI），但俄亥俄州仍有 11 例患者住院，占美国所有 H3N2v 住院患者的 69%。在这些住院的 H3N2v 患者中，有 6 人由于年龄或潜在的医疗条件而处于流感并发症的高风险中，包括迄今为止美国报告的唯一一例与 H3N2v 相关的死亡病例。本报告总结了俄亥俄州 11 例住院 H3N2v 患者的流行病学和临床特征。这些发现加强了对流感并发症高风险人群的建议，即在今年秋天避免在农业展览会上接触猪。此外，对于那些不处于流感并发症高风险中但希望降低感染猪群中流行的流感病毒风险的人，他们也应该在今年秋天的农业展览会上避免接触猪和猪舍。
