Freire-Maia N
Department of Genetics, Federal University of Paraná, Brazil.
Am J Med Genet. 1990 Jan;35(1):115-7. doi: 10.1002/ajmg.1320350121.
Estimates of "relative risks" and "attributable risks" are presented for two Brazilian regions with the lowest (F = 0.00030) and the highest (F = 0.00395) inbreeding levels of the country, and for the whole country (F = 0.00088). The abolition of all consanguineous marriages (from second cousins up to and including uncle-niece/aunt-nephew marriages) in Brazil would eliminate only about 0.22, 3.05, and 0.65% of the "total damage," respectively. "Total damage" is defined as including abortions, miscarriages, stillbirths, infant-juvenile mortality (up to the age of 20 years), and anomalies in the survivors. The reduction of prenatal damage would be 0.11, 1.46, and 0.31%, and that of postnatal damage would be 0.49, 6.65, and 1.36%, respectively.
文中给出了巴西近亲繁殖水平最低（F = 0.00030）、最高（F = 0.00395）的两个地区以及整个巴西（F = 0.00088）的“相对风险”和“归因风险”估计值。在巴西废除所有近亲婚姻（从二级表亲到叔侄/舅甥婚姻）分别只会消除约0.22%、3.05%和0.65%的“总损害”。“总损害”定义为包括流产、死产、死胎、婴幼儿死亡率（至20岁）以及幸存者中的畸形。产前损害的减少分别为0.11%、1.46%和0.31%，产后损害的减少分别为0.49%、6.65%和1.36%。
