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手部关节炎患者近端指间关节置换术:一项荟萃分析。

Proximal interphalangeal joint replacement in patients with arthritis of the hand: a meta-analysis.

作者信息

Adams J, Ryall C, Pandyan A, Metcalf C, Stokes M, Bradley S, Warwick D J

机构信息

University of Southampton, Faculty of Health Sciences, University of Southampton, Southampton SO17 1BJ, UK.

出版信息

J Bone Joint Surg Br. 2012 Oct;94(10):1305-12. doi: 10.1302/0301-620X.94B10.29035.

DOI:10.1302/0301-620X.94B10.29035
PMID:23015553
Abstract

We systematically reviewed all the evidence published in the English language on proximal interphalangeal joint (PIPJ) replacement, to determine its effectiveness on the function of the hand and the associated post-operative complications. Original studies were selected if they reported clinical outcome with a minimum of one year's follow-up. Quality was assessed using the Cowley systematic review criteria modified for finger-joint replacements. Of 319 articles identified, only five were adequately reported according to our quality criteria; there were no randomised controlled trials. PIPJ replacements had a substantial effect size on hand pain of -23.2 (95% confidence interval (CI) -27.3 to -19.1) and grip strength 1.2 (95% CI -10.7 to 13.1), and a small effect on range of movement 0.2 (95% CI -0.4 to 0.8). A dorsal approach was most successful. Post-operative loosening occurred in 10% (95% CI 3 to 30) of ceramic and 12.5% (95% CI 7 to 21) of pyrocarbon replacements. Post-operative complications occurred in 27.8% (95% CI 20 to 37). We conclude that the effectiveness of PIPJ replacement has not been established. Small observational case studies and short-term follow-up, together with insufficient reporting of patient data, functional outcomes and complications, limit the value of current evidence. We recommend that a defined core set of patients, surgical and outcome data for this intervention be routinely and systematically collected within the framework of a joint registry.

摘要

我们系统地回顾了所有以英文发表的关于近端指间关节(PIPJ)置换的证据,以确定其对手功能的有效性及相关术后并发症。如果原始研究报告了至少一年随访期的临床结果,则将其纳入。使用针对手指关节置换修改后的考利系统评价标准评估质量。在识别出的319篇文章中,根据我们的质量标准,只有5篇报告充分;没有随机对照试验。PIPJ置换对手部疼痛的效应量为-23.2(95%置信区间(CI)-27.3至-19.1),对握力的效应量为1.2(95%CI -10.7至13.1),对活动范围的效应较小,为0.2(95%CI -0.4至0.8)。背侧入路最为成功。陶瓷置换术后松动发生率为10%(95%CI 3至30),热解碳置换术后松动发生率为12.5%(95%CI 7至21)。术后并发症发生率为27.8%(95%CI 20至37)。我们得出结论,PIPJ置换的有效性尚未确立。小型观察性病例研究和短期随访,以及患者数据、功能结局和并发症报告不足,限制了当前证据的价值。我们建议在联合登记处的框架内,常规且系统地收集该干预措施明确的核心患者组、手术及结局数据。

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