HomeoDB2：比较同源盒基因数据库的功能扩展，用于进化发育生物学。
HomeoDB2: functional expansion of a comparative homeobox gene database for evolutionary developmental biology.
机构信息
Department of Zoology, University of Oxford, Oxford, UK.
出版信息
Evol Dev. 2011 Nov-Dec;13(6):567-8. doi: 10.1111/j.1525-142X.2011.00513.x.
Abstract
Homeobox gene database (HomeoDB), a manually curated database of homeobox genes and their classification, has been well received since its release in 2008. Here, we report HomeoDB2, an expansion and improvement of the original database that provides greater functionality for the user. HomeoDB2 includes all homeobox loci from 10 animal genomes (human, mouse, chicken, frog, zebrafish, amphioxus, nematode, fruitfly, beetle, honeybee) plus tools for downloading sequences, comparing between species and BLAST searching. HomeoDB2 provides a resource for studying the dynamics of homeobox gene evolution, and is freely accessible at http://homeodb.zoo.ox.ac.uk.
摘要
同源异型盒基因数据库（HomeoDB）是一个经过人工整理的同源异型盒基因及其分类数据库，自 2008 年发布以来受到了广泛欢迎。在这里，我们报告了 HomeoDB2，这是对原始数据库的扩展和改进，为用户提供了更大的功能。HomeoDB2 包含了来自 10 种动物基因组（人类、小鼠、鸡、青蛙、斑马鱼、文昌鱼、线虫、果蝇、甲虫、蜜蜂）的所有同源异型盒基因座，以及用于下载序列、比较物种和 BLAST 搜索的工具。HomeoDB2 为研究同源异型盒基因进化的动态提供了资源，可在 http://homeodb.zoo.ox.ac.uk 免费获取。
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本文引用的文献
1
The dynamics of vertebrate homeobox gene evolution: gain and loss of genes in mouse and human lineages.脊椎动物同源盒基因进化的动态：鼠和人谱系中基因的获得和丢失。
BMC Evol Biol. 2011 Jun 16;11:169. doi: 10.1186/1471-2148-11-169.
2
HomeoDB: a database of homeobox gene diversity.同源异型框基因数据库（HomeoDB）：一个关于同源异型框基因多样性的数据库。
Evol Dev. 2008 Sep-Oct;10(5):516-8. doi: 10.1111/j.1525-142X.2008.00266.x.
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Classification and nomenclature of all human homeobox genes.所有人类同源框基因的分类与命名
BMC Biol. 2007 Oct 26;5:47. doi: 10.1186/1741-7007-5-47.
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The cnidarian-bilaterian ancestor possessed at least 56 homeoboxes: evidence from the starlet sea anemone, Nematostella vectensis.刺胞动物-两侧对称动物的祖先至少拥有56个同源异型框：来自星状海葵（Nematostella vectensis）的证据。
Genome Biol. 2006;7(7):R64. doi: 10.1186/gb-2006-7-7-R64.
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