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“即装即走”与“停留治疗”:通过计算机模拟对院前静脉输液治疗的分析

Load and go versus stay and play: analysis of prehospital i.v. fluid therapy by computer simulation.

作者信息

Wears R L, Winton C N

机构信息

Department of Surgery, University of Florida, Jacksonville.

出版信息

Ann Emerg Med. 1990 Feb;19(2):163-8. doi: 10.1016/s0196-0644(05)81802-5.

DOI:10.1016/s0196-0644(05)81802-5
PMID:2301794
Abstract

A computer-simulation model of prehospital hemorrhage and fluid resuscitation was used to determine under what circumstances it is advantageous to begin fluid resuscitation in the field instead of immediately transporting to the hospital. Four hypothetical bleeding rates (15, 25, 50, and 100 mL/min) were examined for short and long prehospital times. No significant difference in survival was noted for bleeding rates of 15 mL/min for either short or long time; a small but statistically significant increase in survival was noted for bleeding rates of 25 mL/min and long transport times. For both short and long times, all higher bleeding rates showed greater survival with prehospital fluid resuscitation and higher blood pressure at the onset of definitive care.

摘要

一个院前出血与液体复苏的计算机模拟模型被用于确定在何种情况下,在现场开始液体复苏而非立即转运至医院是有利的。针对短和长的院前时间,研究了四种假设的出血速率(15、25、50和100毫升/分钟)。对于15毫升/分钟的出血速率,无论院前时间是短还是长,均未观察到生存率有显著差异;对于25毫升/分钟的出血速率和长转运时间,生存率有小幅但在统计学上显著的提高。对于短和长的院前时间,所有更高的出血速率在院前液体复苏以及确定性治疗开始时具有更高血压的情况下,均显示出更高的生存率。

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Control-oriented physiological modeling of hemodynamic responses to blood volume perturbation.面向控制的血容量扰动血流动力学反应的生理建模
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A Lumped-Parameter Subject-Specific Model of Blood Volume Response to Fluid Infusion.
一种针对个体的血容量对液体输注反应的集总参数模型。
Front Physiol. 2016 Aug 31;7:390. doi: 10.3389/fphys.2016.00390. eCollection 2016.
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Fluid resuscitation in prehospital trauma care: a consensus view.院前创伤护理中的液体复苏:共识观点。
Emerg Med J. 2002 Nov;19(6):494-8. doi: 10.1136/emj.19.6.494.
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Accident and emergency medicine--I.急症医学——I
Postgrad Med J. 1992 Sep;68(803):714-34. doi: 10.1136/pgmj.68.803.714.