Department of Biosciences and Oral Diagnosis, School of Dentistry, Univ Estadual Paulista, São José dos Campos, SP, Brazil.
Braz Oral Res. 2012 Nov-Dec;26(6):523-9. doi: 10.1590/s1806-83242012005000022. Epub 2012 Sep 27.
Volatile sulphur compounds (VSC) are the gases mainly responsible for halitosis (bad breath). The aim of this research was to evaluate the effects of medicinal plants on halitosis control. Two commonly used plants were tested: Curcuma zedoaria and Camellia sinensis (green tea). These plants were prepared as an aqueous solution and used as mouthwashes, compared with a standard mouthwash of 0.12% chlorhexidine gluconate and a placebo (water). The experiment was conducted with 30 volunteers from the School of Dentistry of São Jose dos Campos, Univ. Estadual Paulista - UNESP, SP, Brazil. Each volunteer tested the four mouthwashes. The Cysteine Challenge Method, modified for this study, was used for initial breath standardization. Four breath assessments were conducted after volunteers rinsed orally with acetylcysteine: one before the test mouthwash was used; the second, one minute after its use; a third 90 minutes later; and the last 180 minutes later. The results showed that chlorhexidine gluconate lowered VSC production immediately, and that this effect lasted up to 3 hours, while the tested plants had immediate inhibitory effects but no residual inhibitory effects on VSC. We concluded that Curcuma zedoaria and Camellia sinensis, prepared as infusions and used as mouthwashes, did not have a residual neutralizing effect on VSC.
挥发性含硫化合物（VSC）是主要引起口臭（口腔异味）的气体。本研究旨在评估药用植物对控制口臭的效果。测试了两种常用的植物：姜黄和绿茶（Camellia sinensis）。这些植物被制备成水溶液，用作漱口液，与 0.12%葡萄糖酸氯己定的标准漱口液和安慰剂（水）进行比较。该实验在巴西圣若泽多斯坎波斯大学牙科学院的 30 名志愿者中进行。每位志愿者都测试了四种漱口液。为了本研究，对半胱氨酸挑战法进行了修改，用于初始呼吸标准化。志愿者用乙酰半胱氨酸漱口后，进行了四次呼吸评估：在使用测试漱口液之前进行一次；使用后一分钟进行第二次；使用后 90 分钟进行第三次；使用后 180 分钟进行第四次。结果表明，葡萄糖酸氯己定能立即降低 VSC 的产生，这种效果持续了 3 小时，而测试的植物具有即时抑制作用，但对 VSC 没有残留抑制作用。我们得出结论，姜黄和绿茶制成的浸液用作漱口液，对 VSC 没有残留的中和作用。
