Soares Leo Guimaraes, Guaitolini Roberto Luiz, Weyne Sergio de Carvalho, Falabella Marcio Eduardo Vieira, Tinoco Eduardo Muniz Barretto, da Silva Denise Gomes
Universidade do Estado do Rio de Janeiro, Brazil.
Gen Dent. 2013 Jul;61(4):46-9.
This study sought to evaluate the clinical effect of a mouthrinse containing 0.3% chlorine dioxide (ClO2) in reducing oral volatile sulfur compounds (VSC). Halitosis was induced by L-cysteine in 11 volunteers, and 4 solutions were compared: a test solution containing 0.3% ClO2, 0.07% cetylpyridinium chloride (CPC), and 0.05% sodium fluoride; a placebo; a solution containing 0.05% CPC; and a control solution of 0.2% chlorhexidine gluconate (CHX). VSC levels were assessed using a Halimeter, and 6 measurements were made from baseline to 3 hours postrinse. The VSC reduction rate of the test mouthrinse was superior to the placebo and the CPC solution. There was no difference between the test solution and the CHX solution in VSC reduction rates immediately postrinse, or at 2 and 3 hours postrinse; both solutions were statistically superior to the placebo and the CPC solution.
本研究旨在评估含0.3%二氧化氯（ClO2）的漱口水在减少口腔挥发性硫化合物（VSC）方面的临床效果。通过L-半胱氨酸诱导11名志愿者产生口臭，并比较4种溶液：一种含0.3% ClO2、0.07%西吡氯铵（CPC）和0.05%氟化钠的测试溶液；一种安慰剂；一种含0.05% CPC的溶液；以及一种0.2%葡萄糖酸氯己定（CHX）的对照溶液。使用口气测量仪评估VSC水平，从基线到漱口后3小时进行6次测量。测试漱口水的VSC降低率优于安慰剂和CPC溶液。在漱口后即刻、2小时和3小时，测试溶液与CHX溶液在VSC降低率方面没有差异；两种溶液在统计学上均优于安慰剂和CPC溶液。
