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路易斯碱的阳离子亲合数值。

Cation affinity numbers of Lewis bases.

机构信息

Department of Chemistry, Ludwigs-Maximilians-Universität München, Butenandstr. 5-13, D-81377 München, Germany.

出版信息

Beilstein J Org Chem. 2012;8:1406-42. doi: 10.3762/bjoc.8.163. Epub 2012 Aug 31.

DOI:10.3762/bjoc.8.163
PMID:23019478
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3458768/
Abstract

Using selected theoretical methods the affinity of a large range of Lewis bases towards model cations has been quantified. The range of model cations includes the methyl cation as the smallest carbon-centered electrophile, the benzhydryl and trityl cations as models for electrophilic substrates encountered in Lewis base-catalyzed synthetic procedures, and the acetyl cation as a substrate model for acyl-transfer reactions. Affinities towards these cationic electrophiles are complemented by data for Lewis-base addition to Michael acceptors as prototypical neutral electrophiles.

摘要

利用选定的理论方法，定量研究了一系列路易斯碱与模型阳离子的亲和力。模型阳离子的范围包括作为最小的碳中心亲电试剂的甲基阳离子、苯甲基和三苯甲基阳离子作为路易斯碱催化合成过程中遇到的亲电底物的模型，以及乙酰阳离子作为酰基转移反应的底物模型。与这些阳离子亲电试剂的亲和力与路易斯碱对迈克尔受体的加成数据相补充，迈克尔受体作为典型的中性亲电试剂。

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