Packard M G, White N M
Department of Psychology, McGill University, Montreal, Quebec, Canada.
Behav Neural Biol. 1990 Jan;53(1):39-50. doi: 10.1016/0163-1047(90)90780-a.
Groups of Long-Evans rats with bilateral lesions of the caudate nucleus, sham lesions, or no lesions were given one trial per day in an eight-arm radial maze. The same four maze arms were baited on each trial. The remaining four arms never contained food. Optimal performance required animals to enter each of the baited arms only once on each trial and to avoid entering the arms in the unbaited set. Rats with caudate lesions learned to enter each of the baited arms only once on each trial. However, these rats were severely impaired in learning to avoid entering the arms in the unbaited set. Implications for dual-memory theories are discussed.
对尾状核双侧损伤、假损伤或无损伤的长 Evans 大鼠组，每天在八臂放射状迷宫中进行一次试验。每次试验在相同的四个迷宫臂上放置诱饵。其余四个臂从不放置食物。最佳表现要求动物在每次试验中仅进入每个有诱饵的臂一次，并避免进入未放置诱饵的臂。尾状核损伤的大鼠学会了在每次试验中仅进入每个有诱饵的臂一次。然而，这些大鼠在学习避免进入未放置诱饵的臂方面严重受损。文中讨论了对双记忆理论的影响。
