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一名感染HIV儿童的化脓性汗腺炎

Hidradenitis suppurativa in a HIV-infected child.

作者信息

Prabhu G, Laddha P, Manglani M, Phiske M

机构信息

Department of Pediatrics, Regional Pediatric ART Centre, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, India.

出版信息

J Postgrad Med. 2012 Jul-Sep;58(3):207-9. doi: 10.4103/0022-3859.101403.

DOI:10.4103/0022-3859.101403
PMID:23023355
Abstract

Hidradenitis suppurativa (HS), a painful and chronic condition, commonly occurs in women and coincides with post-pubertal increase in sex hormones. A 13-year-old pre-pubertal HIV-infected male child presented to our clinic with a discharging right axillary lymph node swelling. The biopsy of the lesion showed features of HS. The patient was treated with oral antibiotics, oral steroids, and local antibiotic wash. Though the patient responded to this treatment, the clinical response was not adequate and the lesion recurred. Subsequently, the child was started on antiretroviral therapy (zidovudine, lamivudine, and nevirapine). Following these medications, the lesions healed and had not recurred till we last examined the child. Thus, this is a rare presentation of a known condition in an HIV-infected pre-pubertal male child, which did not respond to usual modalities of treatment and had to be treated with antiretroviral therapy.

摘要

化脓性汗腺炎(HS)是一种疼痛的慢性病症,常见于女性,且与青春期后性激素增加同时出现。一名13岁青春期前感染艾滋病毒的男性儿童因右腋窝淋巴结肿大并有分泌物而前来我们诊所就诊。病变活检显示有HS的特征。该患者接受了口服抗生素、口服类固醇和局部抗生素冲洗治疗。尽管患者对这种治疗有反应,但临床反应并不充分,病变复发。随后,该儿童开始接受抗逆转录病毒治疗(齐多夫定、拉米夫定和奈韦拉平)。服用这些药物后,病变愈合,直到我们最后一次检查该儿童时都未复发。因此,这是一名感染艾滋病毒的青春期前男性儿童中一种已知病症的罕见表现,对常规治疗方式无反应,必须接受抗逆转录病毒治疗。

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