Macca Laura, Moscatt Vittoria, Ceccarelli Manuela, Ingrasciotta Ylenia, Nunnari Giuseppe, Guarneri Claudio
Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Italy C/O A.O.U.P. "Gaetano Martino", via Consolare Valeria 1, 98125 Messina, Italy.
Unit of Infectious Diseases, Department of Clinical and Experimental Medicine, University of Catania, Italy C/O ARNAS "Garibaldi", "Nesima" Hospital, Via Palermo 636, 95122 Catania, Italy.
Biomedicines. 2022 Oct 31;10(11):2761. doi: 10.3390/biomedicines10112761.
Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease of the apocrine glands. Bibliographic search revealed few studies concerning the association between HS and human immunodeficiency virus (HIV). To assess this link, we performed a systematic review of the current knowledge through a careful analysis of the relevant and authoritative medical literature in the field. Results showed that people with HIV are particularly susceptible to developing HS with the characteristic involvement of atypical sites, such as face or thighs, due to HIV-related immunosuppression. Based on the pathogenesis of both conditions and according to our review, we suggest that HIV screening should be routinely performed in suspected cases while monitoring and integrated approach in management are mandatory in the management of HIV-positive patients with HS.
化脓性汗腺炎（HS）是一种累及顶泌汗腺的慢性、使人衰弱的皮肤病。文献检索发现，关于HS与人类免疫缺陷病毒（HIV）之间关联的研究较少。为评估这种联系，我们通过仔细分析该领域相关且权威的医学文献，对现有知识进行了系统综述。结果显示，由于HIV相关的免疫抑制，HIV感染者特别容易患上HS，且具有非典型部位（如面部或大腿）受累的特征。基于这两种疾病的发病机制并根据我们的综述，我们建议在疑似病例中应常规进行HIV筛查，而对于HS合并HIV阳性患者的管理，监测和综合治疗方法是必不可少的。
