通过全血化学发光法测定的既往耶尔森菌关节炎患者氧自由基产生增加。
Increased oxygen radical production determined by whole blood chemiluminescence in patients with previous Yersinia arthritis.
作者信息
Ristola M
机构信息
Department of Bacteriology and Immunology, University of Helsinki, Finland.
出版信息
APMIS. 1990 Feb;98(2):125-30. doi: 10.1111/j.1699-0463.1990.tb01011.x.
Abstract
Luminol-dependent whole blood chemiluminescence (CL) was studied in patients with previous yersinia arthritis (YA). Patients showed significantly higher CL responses compared to healthy controls regardless of HLA-B27 antigen when either N-formyl-methionyl-leucyl-phenylalanine or opsonized zymosan particles were used a stimulus. This hyperreactivity may well play a role in the development of inflammatory injury in YA.
摘要
对既往有耶尔森菌关节炎（YA）的患者进行了鲁米诺依赖的全血化学发光（CL）研究。无论HLA - B27抗原状态如何，当使用N - 甲酰 - 甲硫氨酰 - 亮氨酰 - 苯丙氨酸或调理酵母聚糖颗粒作为刺激物时，患者的CL反应均显著高于健康对照。这种高反应性很可能在YA炎症损伤的发展中起作用。
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