Malviya Ajay, Negi Nitin, Mandora Manish, Yadav J K
Department of Surgery, Dr. S.N. Medical College, Jodhpur, Rajasthan India.
Indian J Surg. 2011 Oct;73(5):346-51. doi: 10.1007/s12262-011-0324-4. Epub 2011 Jun 11.
Opium addiction is rampant in Western Rajasthan and probably has the highest number of opium addicts in the world. The study envisages upon the presentation, diagnosis and various postoperative complications in surgically ill opium addicts vis-à-vis non addicts. The study is purported to benefit clinicians dealing with opium addict patients. The prospective cohort study was conducted at Mahatma Gandhi Hospital, Jodhpur between December 2004 and February 2006 and included cohorts of 71 opium addict and 50 non-addict patients admitted in various surgical wards. The study focused on presentation and the post-surgical complications encountered in these patients vis-à-vis others. The results thus obtained were evaluated statistically (mean±SD, SEM, two tailed t test, chi-square test), p value of <0.05 was considered as significant. A thorough comparative analysis revealed that opium addict patients had a significantly higher incidence of postoperative respiratory, cardiovascular, systemic and local complications. The requirement of analgesics and duration of hospital stay were also significantly higher as compared to control group. The work concludes that opium addicts suffer a much higher degree of postoperative morbidity as compared to non-addicts.
鸦片成瘾在拉贾斯坦邦西部猖獗,这里可能是世界上鸦片成瘾者数量最多的地方。该研究设想了外科手术患病的鸦片成瘾者与非成瘾者在临床表现、诊断及各种术后并发症方面的情况。这项研究旨在使治疗鸦片成瘾患者的临床医生受益。2004年12月至2006年2月期间,在焦特布尔的圣雄甘地医院进行了一项前瞻性队列研究,纳入了在各个外科病房住院的71名鸦片成瘾患者和50名非成瘾患者。该研究聚焦于这些患者与其他患者相比的临床表现及术后并发症。对由此获得的结果进行了统计学评估(均值±标准差、标准误、双尾t检验、卡方检验),p值<0.05被视为具有显著性。全面的对比分析显示,鸦片成瘾患者术后呼吸、心血管、全身及局部并发症的发生率显著更高。与对照组相比,止痛药的需求量和住院时间也显著更长。该研究得出结论,与非成瘾者相比,鸦片成瘾者术后发病率要高得多。