Azarpira N, Ashraf M J, Khademi B, Asadi N
Organ Transplant Research Center, Pathology Department, Nemazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Indian J Otolaryngol Head Neck Surg. 2011 Oct;63(4):349-52. doi: 10.1007/s12070-011-0269-8. Epub 2011 May 15.
Metastatic tumors to the nasal cavity and paranasal sinuses are far less common than primary cancer in this location. Review of the 2004-2010 pathology records of patients with sinonasal malignancy, revealed three cases with distant metastases to this region from primary sites in kidney, prostate and breast. The clinical presentation, histopathological findings and clinical outcome is presented for each patient. Metastases to the nose and paranasal sinuses usually respond poorly to treatment and have a poor prognosis. This report highlights the importance of suspecting metastases in patients with a previous history of malignancy. Therefore, thorough history and clinical evaluation is mandatory in any known/treated case of cancer.
鼻腔和鼻窦的转移性肿瘤远比该部位的原发性癌症少见。回顾2004年至2010年鼻窦恶性肿瘤患者的病理记录,发现3例患者从肾脏、前列腺和乳腺的原发部位远处转移至该区域。本文介绍了每位患者的临床表现、组织病理学检查结果及临床结局。鼻腔和鼻窦转移瘤通常对治疗反应不佳,预后较差。本报告强调了怀疑有恶性肿瘤病史患者存在转移的重要性。因此,对于任何已知/已治疗的癌症病例,详细的病史和临床评估都是必不可少的。