Department of Neurology, Division of Clinical Neurophysiology, Mayo Clinic, Rochester, MN, USA.
J Clin Neurophysiol. 2012 Oct;29(5):379-84. doi: 10.1097/WNP.0b013e31826b3c7c.
Dorsolateral frontal lobe seizures often present as a diagnostic challenge. The diverse semiologies may not produce lateralizing or localizing signs and can appear bizarre and suggest psychogenic events. Unfortunately, scalp electroencephalographic (EEG) and magnetic resonance imaging (MRI) are often unsatisfactory. It is not uncommon that these traditional diagnostic studies are either unhelpful or even misleading. In some cases, SPECT and positron emission tomography imaging can be an effective tool to identify the origin of seizures. However, these techniques and other emerging techniques all have limitations, and new approaches are needed to improve source localization.
额外侧额叶癫痫发作常构成诊断挑战。其多种多样的症状学表现可能不产生偏侧化或局灶性体征,并且可能显得怪异而提示为心因性事件。不幸的是,头皮脑电图(EEG)和磁共振成像(MRI)通常不令人满意。这些传统的诊断研究常常无用或甚至误导并不少见。在某些情况下,SPECT 和正电子发射断层扫描成像可以是识别癫痫起源的有效工具。然而,这些技术和其他新兴技术都有其局限性,需要新的方法来改善源定位。