Department of Neurology, Prasat Neurological Institute, Bangkok, Thailand.
J Clin Neurophysiol. 2012 Oct;29(5):371-8. doi: 10.1097/WNP.0b013e31826b3c60.
Mesial frontal lobe epilepsies can be divided into epilepsies arising from the anterior cingulate gyrus and those of the supplementary sensorimotor area. They provide diagnostic challenges because they often lack lateralizing or localizing features on clinical semiology and interictal and ictal scalp electroencephalographic (EEG) recordings. A number of unique semiologic features have been described over the last decade in patients with mesial frontal lobe epilepsy (FLE). There are few reports of applying advanced neurophysiologic techniques such as electrical source imaging, magnetoencephalography, EEG/functional magnetic resonance imaging, or analysis of high-frequency oscillations in patients with mesial FLE. Despite these diagnostic challenges, it seems that patients with mesial FLE benefit from epilepsy surgery to the same extent or even better than patients with FLE do, as a whole.
额内侧额叶癫痫可分为起源于扣带回前部的癫痫和补充感觉运动区的癫痫。由于在临床半影和发作间期和发作期头皮脑电图（EEG）记录中缺乏偏侧化或定位特征，它们带来了诊断挑战。在过去十年中，已有多项关于额内侧额叶癫痫（FLE）患者独特半影特征的报道。很少有报道应用电源成像、脑磁图、EEG/功能磁共振成像或高频振荡分析等先进神经生理技术在额内侧 FLE 患者中应用。尽管存在这些诊断挑战，但似乎内侧 FLE 患者从癫痫手术中获益的程度与 FLE 患者一样，甚至更好。
