海马体的体内显微内窥镜检查。
In vivo microendoscopy of the hippocampus.
作者信息
Barretto Robert P J, Schnitzer Mark J
出版信息
Cold Spring Harb Protoc. 2012 Oct 1;2012(10):1092-9. doi: 10.1101/pdb.prot071472.
Abstract
Conventional intravital microscopy has generally been limited to superficial brain areas such as the olfactory bulb, the neocortex, or the cerebellar cortex. In vivo optical microendoscopy uses gradient refractive index (GRIN) microlenses that can be inserted into tissue to image cells in deeper areas. This protocol describes in vivo microendoscopy of the mouse hippocampus. The general methodology can be applied to many deep brain regions and other areas of the body.
摘要
传统的活体显微镜检查通常局限于诸如嗅球、新皮层或小脑皮层等浅表脑区。体内光学显微内窥镜检查使用梯度折射率（GRIN）微透镜，这些微透镜可以插入组织中以对更深区域的细胞进行成像。本方案描述了小鼠海马体的体内显微内窥镜检查。一般方法可应用于许多深部脑区和身体的其他部位。
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