芦荟凝胶与曲安奈德软膏治疗口腔扁平苔藓的随机试验
Randomized trial of aloe vera gel vs triamcinolone acetonide ointment in the treatment of oral lichen planus.
作者信息
Reddy Reddy Lavanya, Reddy Reddy Sudhakara, Ramesh Tatapudi, Singh Thakuri Rajesh, Swapna Lingam Amara, Laxmi Nimma Vijaya
机构信息
Department of Oral Medicine and Radiology, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
出版信息
Quintessence Int. 2012 Oct;43(9):793-800.
OBJECTIVE
To determine the effectiveness of aloe vera gel in the treatment of oral lichen planus when compared with triamcinolone acetonide.
METHOD AND MATERIALS
A randomized, double-blind, clinical trial was designed. The study sample constituted 40 patients (23 males and 17 females) who were randomly divided into two equal groups. Group A patients received aloe vera gel, while group B patients received triamcinolone acetonide.
RESULTS
Forty patients were included in the study. Most of the sample presented with erosive (n = 18) and atrophic (n = 14) variants of oral lichen planus. When clinical signs and symptoms were observed after 8 weeks of therapy, it was determined that aloe vera gel was more effective than triamcinolone acetonide in the treatment of oral lichen planus.
CONCLUSION
Aloe vera gel can be considered a safe alternative treatment for oral lichen planus.
目的
与曲安奈德相比，确定芦荟凝胶治疗口腔扁平苔藓的有效性。
方法和材料
设计了一项随机、双盲临床试验。研究样本包括40例患者（23例男性和17例女性），他们被随机分为两组，每组人数相等。A组患者接受芦荟凝胶治疗，而B组患者接受曲安奈德治疗。
结果
40例患者纳入研究。大多数样本表现为糜烂型（n = 18）和萎缩型（n = 14）口腔扁平苔藓。治疗8周后观察临床体征和症状时，确定芦荟凝胶在治疗口腔扁平苔藓方面比曲安奈德更有效。
结论
芦荟凝胶可被视为口腔扁平苔藓的一种安全替代治疗方法。
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